Providence, RINCT05988632Now EnrollingIRB Ready

Alcohol Use Disorder Clinical Trial in Providence, RI

Access cutting-edge alcohol use disorder treatment through this phase 1/2 clinical trial at a research site in Providence. Study-provided care at no cost to qualified participants.

Sponsored by Brown University

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Expert Care in Providence

Access alcohol use disorder specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related alcohol use disorder treatment provided free

Apply for This Providence Location

Check if you qualify for this alcohol use disorder clinical trial in Providence, RI

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Providence

    Convenient for RI residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Providence site if eligible
  4. 4Begin participation

About This Alcohol Use Disorder Study in Providence

This is a randomized controlled trial (RCT), within-subject, crossover, double-blind, placebo-controlled in non-treatment-seeking individuals with Alcohol Use Disorder (AUD) (N=40, 50% female) randomized to IN insulin or placebo. In a bar laboratory setting, randomized participants will receive a single dose of IN insulin (80IU) or an IN matched placebo (0.9% Saline). Participants will undergo a cue-reactivity paradigm followed by an alcohol challenge that includes an alcohol drink designed to raise the breath alcohol content (BrAC) to 0.08g/dL.

Sponsor: Brown University

Who Can Participate

Inclusion Criteria

meet any DSM-5 criteria score for AUD
Individuals who, in the last month, have consumed at least the same amount of alcohol that will be administered in the laboratory procedure (i.e. to reach BrAC levels of 0.08g/dl, \~two drinks in one occasion)
BrAC=0.00g/dL at each visit
good health as confirmed by medical history, physical examination and lab tests
willing to adhere to the study procedures
understand informed consent and questionnaires in English at an 8th grade level
willing to have glucose monitored by finger stick during the laboratory procedures

Exclusion Criteria

• female identifying who are breastfeeding or pregnant (assessed by a urine screen)
individuals with diabetes
history of suicide attempts in the last three years
current diagnosis of other substance use disorder (other than nicotine or cannabis)
use of drugs (e.g. stimulants/opioids) at each alcohol administration session (by urine tox screen)
cannabis intoxication (by clinical assessments)
use of medications that may interact with insulin and alcohol (by Micromedex database)
hypersensitivity to insulin
any nasal disease/congestion that may interfere with intranasal drug absorption;
baseline hypoglycemia (blood glucose ≤65mg/dL) or hyperglycemia (blood glucose \>200mg/dL) (by finger stick)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Providence?

Yes, this clinical trial (NCT05988632) has an active research site in Providence, RI that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Alcohol Use Disorder Treatment Options in Providence, RI

If you're searching for alcohol use disorder treatment options in Providence, RI, this clinical trial (NCT05988632) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Providence research site is actively enrolling participants for this phase 1/2 clinical trial. You'll receive care from experienced alcohol use disorder specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all alcohol use disorder clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Providence, RI