Santa Barbara, CANCT07871071Now EnrollingIRB Ready

Amyotrophic Lateral Sclerosis Clinical Trial in Santa Barbara, CA

Access cutting-edge amyotrophic lateral sclerosis treatment through this clinical trial at a research site in Santa Barbara. Study-provided care at no cost to qualified participants.

Sponsored by Cognixion

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Expert Care in Santa Barbara

Access amyotrophic lateral sclerosis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related amyotrophic lateral sclerosis treatment provided free

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Check if you qualify for this amyotrophic lateral sclerosis clinical trial in Santa Barbara, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Santa Barbara

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Santa Barbara site if eligible
  4. 4Begin participation

About This Amyotrophic Lateral Sclerosis Study in Santa Barbara

This study compares a wearable brain-computer interface (BCI) communication device with the eye-tracking communication devices that people with ALS already use. As ALS progresses, speech is lost and many people come to rely on an eye-tracking speech generating device. Eye-tracking performance can decline as oculomotor control is affected, and some people reach a point where it no longer works reliably for them. The Cognixion ONE device adds a brain-computer interface input, which does not depend on eye movement, alongside an AI-assisted communication application. Thirty adults with ALS who currently use a Tobii Dynavox or Smartbox eye-tracking device will take part. Each participant uses three communication options at home over a 12-week period: their own eye-tracking device, the Cognixion ONE device with a head-worn augmented-reality display, and the Cognixion ONE device with a screen-based display. For some sessions the option is assigned; for others the participant chooses. The main measure is how much time participants voluntarily choose to spend using each option. That choice is treated as the clearest signal of which option genuinely works better for them. The study also measures communication speed and accuracy, usability, workload, quality of life, and caregiver burden. The Cognixion ONE device is an investigational research device. It is not approved or cleared by the U.S. Food and Drug Administration for any medical use.

Sponsor: Cognixion

Who Can Participate

Inclusion Criteria

Diagnosis of ALS established by a neurologist, meeting either the Gold Coast Criteria (preferred) or the revised El Escorial criteria (definite, probable, probable laboratory-supported, or possible ALS), documented by the referring or treating neurologist
ALSFRS-R Speech subscale score of 3 or lower (impaired but functional speech) through 0 (anarthric)
Documented use of a Tobii Dynavox or Smartbox eye-gaze speech generating device as primary or secondary communication method for at least 30 days prior to screening. Candidates who meet all other criteria but lack a prescribed eye-gaze device may be provided a loaner device, capped at 25 percent of the enrolled cohort
Age 18 years or older
A designated, trainable caregiver able to be present for structured study sessions and to complete a 2-hour onboarding and a Month-3 refresher
Volitional eye opening sustained independently for at least 30 minutes, and sufficient visual function to perceive the augmented-reality display stimuli
A reliable communication method other than the study device for affirmative assent, at minimum a yes/no channel via residual vocalization, head movement, blink, or brow raise
Sufficient English comprehension to engage with the study protocol and the AI conversational interface

Exclusion Criteria

Active hospice enrollment without documented capacity to participate in research activities
Cognitive or behavioral impairment of a degree that would preclude successful participation in study procedures, as judged by the treating neurologist, a study neurologist, or the study speech-language pathologist
History of photosensitive epilepsy or active seizure disorder
Sensitivity to flashing lights
Severe uncorrected visual impairment that precludes use of an augmented-reality display
Vision disorders restricting the visual field, such as glaucoma with significant field loss, diplopia, or nystagmus
History of vertigo or other vestibular disorders that would be aggravated by augmented-reality display use
Claustrophobia related to head-mounted display use, after attempted accommodation
Scalp condition prone to irritation, inflammation, injury, or infectious process that precludes safe placement of EEG electrodes
Severe oculomotor impairment that precludes establishment of an initial eye-gaze calibration on the participant's existing eye-gaze device
Concurrent enrollment in another investigational communication-device or brain-computer interface trial
Severe hearing impairment or deafness that would prevent participation in conversational tasks

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Santa Barbara?

Yes, this clinical trial (NCT07871071) has an active research site in Santa Barbara, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Amyotrophic Lateral Sclerosis Treatment Options in Santa Barbara, CA

If you're searching for amyotrophic lateral sclerosis treatment options in Santa Barbara, CA, this clinical trial (NCT07871071) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Santa Barbara research site is actively enrolling participants for this clinical trial. You'll receive care from experienced amyotrophic lateral sclerosis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all amyotrophic lateral sclerosis clinical trials near you to find additional studies recruiting in your area.

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