Columbia, MONCT07290062Now EnrollingIRB Ready

Amyotrophic Lateral Sclerosis Clinical Trial in Columbia, MO

Access cutting-edge amyotrophic lateral sclerosis treatment through this phase 1 clinical trial at a research site in Columbia. Study-provided care at no cost to qualified participants.

Sponsored by Insmed Gene Therapy LLC

Quick Self-Assessment

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Expert Care in Columbia

Access amyotrophic lateral sclerosis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related amyotrophic lateral sclerosis treatment provided free

Apply for This Columbia Location

Check if you qualify for this amyotrophic lateral sclerosis clinical trial in Columbia, MO

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Columbia

    Convenient for MO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Columbia site if eligible
  4. 4Begin participation

About This Amyotrophic Lateral Sclerosis Study in Columbia

The primary objective of this dose-finding study is to evaluate the safety, tolerability and pharmacodynamics of single dose of INS1202 via IT administration in participants ≥ 18 to \<80 years of age with ALS who carry superoxide dismutase type 1 (SOD1) mutations or harbor no known ALS-related genetic mutation.

Sponsor: Insmed Gene Therapy LLC

Who Can Participate

Inclusion Criteria

Participant with body mass index (BMI) ≥18 kilograms per square meter (kg/m\^2).
Participant with symptomatic ALS as diagnosed by Gold Coast diagnostic criteria.
Sporadic ALS cohorts: Negative testing for known monogenic mutations associated with familial ALS.
SOD1-ALS (Cohorts 2 and 3 only): Confirmed pathogenic SOD1 mutation, with negative testing for other genetic mutations associated with familial ALS.
Any polymorphism or mutation in the coding region will require additional review by the Sponsor to determine compatibility with the study intervention.
Baseline ALSFRS-R ≥ 24.
ALS disease duration ≤ 42 months. Key

Exclusion Criteria

Previous treatment for ALS with cellular or gene therapies.
Any investigational medication or treatment (for ALS or other condition). Note: Other protocol-defined inclusion/exclusion criteria may apply.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Columbia?

Yes, this clinical trial (NCT07290062) has an active research site in Columbia, MO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Amyotrophic Lateral Sclerosis Treatment Options in Columbia, MO

If you're searching for amyotrophic lateral sclerosis treatment options in Columbia, MO, this clinical trial (NCT07290062) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Columbia research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced amyotrophic lateral sclerosis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all amyotrophic lateral sclerosis clinical trials near you to find additional studies recruiting in your area.

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