Philadelphia, PANCT04959474Now EnrollingIRB Ready

Anatomic Stage 0 Breast Cancer AJCC v8 Clinical Trial in Philadelphia, PA

Access cutting-edge anatomic stage 0 breast cancer ajcc v8 treatment through this clinical trial at a research site in Philadelphia. Study-provided care at no cost to qualified participants.

Sponsored by Thomas Jefferson University

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Expert Care in Philadelphia

Access anatomic stage 0 breast cancer ajcc v8 specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related anatomic stage 0 breast cancer ajcc v8 treatment provided free

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Check if you qualify for this anatomic stage 0 breast cancer ajcc v8 clinical trial in Philadelphia, PA

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Why Participate?

  • No-Cost Study Care

  • Local to Philadelphia

    Convenient for PA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Philadelphia site if eligible
  4. 4Begin participation

About This Anatomic Stage 0 Breast Cancer AJCC v8 Study in Philadelphia

This phase II trial studies the effect of calorie reduction while undergoing stereotactic ablative radiation therapy in treating patients with breast cancer. Stereotactic ablative radiation therapy (sABR) is a highly focused radiation treatment that gives an intense dose of radiation concentrated on a tumor, while limiting the dose to the surrounding organ. Giving SABR before surgery may make the tumor smaller. Adding dietary restrictions in combination with radiation therapy may help increase local control and decrease the spread of the cancer to other places in the body. The purpose of this trial is to identify if there is a decrease in tumor tissue in patients undergoing caloric restriction during pre-operative SABR, compared to patients undergoing pre-operative SABR alone.

Sponsor: Thomas Jefferson University

Who Can Participate

Inclusion Criteria

• Patients with pathologically proven DCIS or invasive breast cancer histologies
Willing and able to provide informed consent
Willing and able to comply with study treatments including dietary intervention
Body mass index (BMI) \>= 21 at time of enrollment
Age \>= 40 years at time of consent \
Patients with triple negative breast cancer (TNBC) must be \>= 50 years of age at time of consent
Karnofsky performance status (KPS) score 70 - 100
Tumor size =\< 3.0 cm
Gross disease within the breast must be unifocal \
Gross disease may be multifocal as long as the total extent of tumor, gross and microscopic, occupies a volume with greatest dimension =\< 3 cm
Patients with invasive disease are required to have clinical axillary staging including axillary ultrasound (US) that proves patient is clinically node negative or can be done by physical examination if the patient is over 70
Patient is not being considered for preoperative chemotherapy
Must be English or Spanish speaking

Exclusion Criteria

Patient is clinically node positive: clinically suspicious axillary lymph node(s) by axillary US or exam unless biopsied and found to be negative
Patient has stage IV metastatic disease \
Patients with oligo-metastatic disease who are being treated with curative intent per the treating physician will not be excluded if all other eligibility criteria are met
Breast tumor size is \> 3.0 cm
Positive non-axillary sentinel nodes or evidence of suspicious supraclavicular, infraclavicular, or internal mammary nodes by imaging or physical exam, unless biopsied and found to be negative for tumor
Evidence by physical examination or mammography of other suspicious masses, densities, or microcalcifications in either breast, unless biopsied and found to be benign
Paget's disease of the nipple
Previous breast radiation on ipsilateral side
Any prior treatment with radiation therapy or chemotherapy for the current breast cancer diagnosis prior to registration
Patients with significant psychiatric illness that would preclude them from adhering to the protocol in the judgement of the treating clinician
BMI \< 21 at the time of study enrollment

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Philadelphia?

Yes, this clinical trial (NCT04959474) has an active research site in Philadelphia, PA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Anatomic Stage 0 Breast Cancer AJCC v8 Treatment Options in Philadelphia, PA

If you're searching for anatomic stage 0 breast cancer ajcc v8 treatment options in Philadelphia, PA, this clinical trial (NCT04959474) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Philadelphia research site is actively enrolling participants for this clinical trial. You'll receive care from experienced anatomic stage 0 breast cancer ajcc v8 specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all anatomic stage 0 breast cancer ajcc v8 clinical trials near you to find additional studies recruiting in your area.

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