Los Angeles, CANCT04889872Now EnrollingIRB Ready

Aortic Stenosis, Calcific Clinical Trial in Los Angeles, CA

Access cutting-edge aortic stenosis, calcific treatment through this clinical trial at a research site in Los Angeles. Study-provided care at no cost to qualified participants.

Sponsored by Edwards Lifesciences

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Expert Care in Los Angeles

Access aortic stenosis, calcific specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related aortic stenosis, calcific treatment provided free

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Check if you qualify for this aortic stenosis, calcific clinical trial in Los Angeles, CA

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Why Participate?

  • No-Cost Study Care

  • Local to Los Angeles

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Los Angeles site if eligible
  4. 4Begin participation

About This Aortic Stenosis, Calcific Study in Los Angeles

This study objective is to establish the safety and effectiveness of the Edwards SAPIEN 3 / SAPIEN 3 Ultra / SAPIEN 3 Ultra RESILIA Transcatheter Heart Valve systems in subjects with moderate, calcific aortic stenosis. Following completion of enrollment, subjects will be eligible for enrollment in the continued access phase of the trial.

Sponsor: Edwards Lifesciences

Who Can Participate

Inclusion Criteria

65 years of age or older at time of randomization
Moderate aortic stenosis
Subject has symptoms or evidence of cardiac damage/dysfunction
The subject or subject's legal representative has been informed of the nature of the study, agrees to its provisions, and has provided written informed consent. Key

Exclusion Criteria

Native aortic annulus size unsuitable for the THV
Anatomical characteristics that would preclude safe transfemoral placement of the introducer sheath or safe passage of the delivery system
Aortic valve is unicuspid or non-calcified
Bicuspid aortic valve with an aneurysmal ascending aorta \> 4.5 cm or severe raphe/leaflet calcification
Pre-existing mechanical or bioprosthetic aortic valve
Severe aortic regurgitation
Prior balloon aortic valvuloplasty to treat severe AS
LVEF \< 20%
Left ventricular outflow tract calcification that would increase the risk of annular rupture or significant paravalvular leak post-TAVR
Cardiac imaging evidence of intracardiac mass, thrombus, or vegetation
Coronary or aortic valve anatomy that increases the risk of coronary artery obstruction post-TAVR

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Los Angeles?

Yes, this clinical trial (NCT04889872) has an active research site in Los Angeles, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Aortic Stenosis, Calcific Treatment Options in Los Angeles, CA

If you're searching for aortic stenosis, calcific treatment options in Los Angeles, CA, this clinical trial (NCT04889872) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Los Angeles research site is actively enrolling participants for this clinical trial. You'll receive care from experienced aortic stenosis, calcific specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all aortic stenosis, calcific clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Los Angeles, CA