Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Valvular Heart Disease Clinical Trials
Valvular Heart Disease clinical trials are recruiting across 83 cities. Here are the cities with the most active studies:
Valvular Heart Disease Trial Phases
33 research organizations are sponsoring valvular heart disease trials.
About Valvular Heart Disease
Valvular heart disease occurs when one or more heart valves do not function properly, disrupting blood flow through the heart. Common types include aortic stenosis and mitral regurgitation. Treatment ranges from monitoring to surgical valve repair or replacement.
Clinical trials are advancing new treatments for valvular heart disease. Currently, 40 studies are recruiting a combined 53,032 participants across the United States. Research is being conducted by 33 organizations including Montreal Heart Institute, Duk-Woo Park, MD, University of British Columbia and 30 others.
2026 Valvular Heart Disease Research Landscape
As of July 2026, the valvular heart disease clinical trial landscape includes 40 actively recruiting studies across 83 cities in the United States. These studies are collectively seeking 53,032 participants, with an average enrollment target of 1,326 per study.
The research spans multiple phases of development: 17 studies are in NA, 2 studies are in PHASE2, 2 studies are in PHASE1, 2 studies are in PHASE4. Early-phase studies suggest new therapeutic approaches are being explored for valvular heart disease.
Research is being led by 33 different organizations, including Montreal Heart Institute, Duk-Woo Park, MD, University of British Columbia, Edwards Lifesciences, Mayo Clinic, and 28 others. The large number of sponsors reflects significant research interest and investment in valvular heart disease treatment advancement.
Geographically, valvular heart disease trials are most concentrated in Los Angeles, California (9 trials); Phoenix, Arizona (8 trials); San Francisco, California (8 trials); New York, New York (7 trials); Atlanta, Georgia (7 trials) and 7 other cities.
Featured Valvular Heart Disease Studies
Highlighted recruiting studies for valvular heart disease, selected by enrollment size and research scope.
Enhanced Valves Interventions and Safe AI Generated End Results
This non-interventional study aims to use artificial intelligence to improve the prediction of transcatheter heart valve interventions and optimize patient outcomes. It is based on the analysis of retrospective data from various specialized centers worldwide.
Transpacific TAVR Registry
This registry evaluates the long-term outcome of Transcatheter aortic valve replacement (TAVR) in real-world clinical practice.
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement
Patients undergoing transcatheter aortic valve replacement (TAVR) often have concomitant coronary artery disease (CAD) which may adversely affect prognosis. There is uncertainty about the benefits and the optimal timing of revascularization for such patients. There is currently clinical equipoise regarding the management of concomitant CAD in patients undergoing TAVR. Some centers perform routine ...
Frequently Asked Questions About Valvular Heart Disease Clinical Trials
Are there valvular heart disease clinical trials near me?
Yes, there are 40 valvular heart disease clinical trials currently recruiting across 83+ cities in the United States, including Los Angeles, California; Phoenix, Arizona; San Francisco, California. Browse the studies above to find one at a location convenient for you.
How do I join a valvular heart disease clinical trial?
To join a valvular heart disease clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are valvular heart disease clinical trials free?
Yes, participation in valvular heart disease clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of valvular heart disease treatments are being studied?
Current valvular heart disease clinical trials are testing a range of approaches across NA (17 studies), PHASE2 (2 studies), PHASE1 (2 studies), PHASE4 (2 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 33 research organizations.
Is it safe to participate in valvular heart disease clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 15, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 15, 2026 · Data from ClinicalTrials.gov