Salt Lake City, UTNCT07767097Now EnrollingIRB Ready

Arthrofibrosis of Knee Clinical Trial in Salt Lake City, UT

Access cutting-edge arthrofibrosis of knee treatment through this clinical trial at a research site in Salt Lake City. Study-provided care at no cost to qualified participants.

Sponsored by Mount Sinai Hospital, Canada

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Expert Care in Salt Lake City

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related arthrofibrosis of knee treatment provided free

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Check if you qualify for this arthrofibrosis of knee clinical trial in Salt Lake City, UT

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Why Participate?

  • No-Cost Study Care

  • Local to Salt Lake City

    Convenient for UT residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Salt Lake City site if eligible
  4. 4Begin participation

About This Arthrofibrosis of Knee Study in Salt Lake City

Acquired idiopathic stiffness (AIS) is a common complication following total knee arthroplasty (TKA). It is caused by excessive scar formation, which leads to pain, loss of motion, and functional impairment. When early noninvasive treatments fail, some patients require more surgery. In these cases, surgeons often use a special type of replacement called a hinged prosthesis, which allows more thorough removal of scar tissue and stiffened ligaments. Unfortunately, even after more surgery, many patients continue to struggle with stiffness, pain, and impaired function. Low-dose irradiation (LDI) is a safe, established therapy for conditions with abnormal scar formation. Its role in the setting of AIS has not been defined. The goal of this study is to compare outcomes of revision TKA with or without the addition of LDI. The primary outcome is range of motion at one year following surgery. Secondary outcomes include patient-reported functional scores, repeat surgeries, and complications like wound breakdown or infection. This project has the potential to address a common, debilitating complication after TKA, improve outcomes, reduce repeat interventions and healthcare costs, and broader implementation and standardization of care.

Sponsor: Mount Sinai Hospital, Canada

Who Can Participate

Inclusion Criteria

Adults (≥18 years) undergoing revision TKA with a hinged prosthesis for AIS after primary TKA
Patient with a ROM arc \<70 degrees or flexion contracture of \>20 degrees without any identifiable cause for stiffness (e.g. component oversizing, malrotation, infection, or periprosthetic fracture).

Exclusion Criteria

Revision for causes other than AIS (e.g., component malposition, infection, periprosthetic fracture)
Prior ipsilateral knee infection
Revision to non-hinged prosthesis
Medical contraindications to surgery
Medical contraindications to irradiation
Currently pregnant or planning to become pregnant during the study period

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Salt Lake City?

Yes, this clinical trial (NCT07767097) has an active research site in Salt Lake City, UT that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Arthrofibrosis of Knee Treatment Options in Salt Lake City, UT

If you're searching for arthrofibrosis of knee treatment options in Salt Lake City, UT, this clinical trial (NCT07767097) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Salt Lake City research site is actively enrolling participants for this clinical trial. You'll receive care from experienced arthrofibrosis of knee specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all arthrofibrosis of knee clinical trials near you to find additional studies recruiting in your area.

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