Nashville, TNNCT06964269Now EnrollingIRB Ready

Autoimmune Diseases Clinical Trial in Nashville, TN

Access cutting-edge autoimmune diseases treatment through this clinical trial at a research site in Nashville. Study-provided care at no cost to qualified participants.

Sponsored by Toyos Clinic

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Expert Care in Nashville

Access autoimmune diseases specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related autoimmune diseases treatment provided free

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Check if you qualify for this autoimmune diseases clinical trial in Nashville, TN

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Nashville

    Convenient for TN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Nashville site if eligible
  4. 4Begin participation

About This Autoimmune Diseases Study in Nashville

Single-site, open label pilot study of 20 autoimmune patients diagnosed with dry eye demonstrating via the proparacaine challenge some peripheral corneal pain component. At least 16 patients will receive and complete 12 weeks of 80 units of Acthar Gel to be injected subcutaneously twice weekly via Acthar Gel single-dose pre-filled SelfJectTM injector (SelfJect) to assess the effects on subjective sensation of ocular pain, conjunctival and corneal staining, in vivo assessments of corneal nerves as measured by confocal imaging, VAS scales of common neuropathic pain symptoms and comfort of SelfJect will be assessed.

Sponsor: Toyos Clinic

Who Can Participate

Inclusion Criteria

Subject can read, understand, sign and informed consent.
Provision of signed and dated informed consent form and HIPPA authorization.
Stated willingness to comply with all study procedures and availability
for the duration of the study
Male or female aged 18-85 years.
Normal eyelid anatomy
Patients diagnosed with dry eye for at least 6 months prior to enrollment.
Patients with Symptom Bother score at Baseline of 50.6 or greater.
Patients with a diagnosis of any autoimmune disease.
Patients with one or more corneal neuroma as seen on baseline confocal microscopy.
Patients with partial or total relief of corneal pain with one drop of proparacaine over 15 minutes post-instillation.
No prior use of Acthar Gel SelfJect or otherwise for any indication.

Exclusion Criteria

1\. Have a known hypersensitivity or contraindication to the investigational product or their components. 2\. Unwilling to participate in study activities or report for study visits. 3. Current pregnancy or lactation per self-report. Patients who are unwilling to use an effective method of birth control while participating in the study and for four weeks after the last dose of study drug is administered. 4\. Use of antihistamines, mast cell stabilizers, or prescription eye drops within 24 hours prior to screening and for the study, unless the dose has been stable for 14 days. 5\. Current use of cenegermin, topical nerve growth factor or platelet rich plasma or use within the past 30 days. 6\. Treatment with another investigational drug or other intervention within 30 days of screening. 7\. Have serious or severe disease or uncontrolled medical condition that in the judgement of the investigator could confound study assessments, limit compliance, or pose safety risks. 8\. Systemic medications known to cause dry eye should not be used including antimuscarinics, antihistamines, vitamin A analogs, antianxiety agents, and others unless stable for at least 30 days.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Nashville?

Yes, this clinical trial (NCT06964269) has an active research site in Nashville, TN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Autoimmune Diseases Treatment Options in Nashville, TN

If you're searching for autoimmune diseases treatment options in Nashville, TN, this clinical trial (NCT06964269) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Nashville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced autoimmune diseases specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all autoimmune diseases clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Nashville, TN