Boston, MANCT07211217Now EnrollingIRB Ready

Bipolar Disorder (BD) Clinical Trial in Boston, MA

Access cutting-edge bipolar disorder (bd) treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Massachusetts General Hospital

Quick Self-Assessment

See if you qualify for this Boston location

Preparing your pre-screening questions…

Expert Care in Boston

Access bipolar disorder (bd) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related bipolar disorder (bd) treatment provided free

Apply for This Boston Location

Check if you qualify for this bipolar disorder (bd) clinical trial in Boston, MA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Bipolar Disorder (BD) Study in Boston

This is a randomized controlled trial investigating the effects of an 8-TRE intervention compared to a wait list (control) on metabolic health and body composition in people diagnosed with BD and who are currently obese and at least mildly depressed. Following a 1-week baseline assessment, participants will be randomized to either a TRE or the wait list (1-to-1 ratio) for 8 weeks. At baseline, Week 8 (post treatment), and Week 20 (follow-up), investigators will assess daily eating patterns for one week, followed by collection of fasting lipids, body weight and vital signs. At Week 4 (i.e., mid-treatment), the investigators will assess self-reported outcomes only. Participants assigned to the wait list condition will have the option of receiving the TRE intervention after 20 weeks.

Sponsor: Massachusetts General Hospital

Who Can Participate

Inclusion Criteria

Adults (aged 18-65 years)
Diagnosed with bipolar disorder (i.e., subtype Bipolar I or II as assessed with the Quick SCID)21
Currently experiencing depression (i.e., PHQ-9 ≥ 10)22
Currently overweight (i.e., Body mass index (BMI) \> 30 kg/m2)
Provides Informed Consent

Exclusion Criteria

Dietary factors:
Diagnosis, or strong clinical suspicion, of eating disorders, including but not limited to, anorexia nervosa, bulimia nervosa, binge eating disorder (as assessed with the Quick SCID)
Concurrent dietary intervention or modification unrelated to study procedures
Psychiatric factors:
Severe depression (i.e., PHQ-9\>20)
Experiencing manic symptoms (i.e., ASRM \< 6)23
Active suicidal ideation (i.e., PHQ-9, item 9 \>2)
Current alcohol/substance use disorder (as assessed with the Quick SCID)
Medical factors:
Use of weight loss medications or supplements
Use of medications that may cause weight loss or gain, unless body weight and medication usage remained stable for at least 6 months
Previous weight loss surgery
Malignancy within past 2 years
Major surgery within past 3 months
Medical instability considered to interfere with study procedures
Use of medications that have the potential to cause hypoglycemia (e.g., insulin, sulfonylureas)
Undergoing treatment for cancer
Use of medications for which time restricted eating would interfere with recommended timing of medication ingestion with food intake.
Lifestyle and other factors: a. Work or social schedules that would impede ability to adhere to study protocol
Adherence factors:
Ability to adhere to study procedures

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT07211217) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Bipolar Disorder (BD) Treatment Options in Boston, MA

If you're searching for bipolar disorder (bd) treatment options in Boston, MA, this clinical trial (NCT07211217) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced bipolar disorder (bd) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all bipolar disorder (bd) clinical trials near you to find additional studies recruiting in your area.

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