Orange, CANCT07827001Now EnrollingIRB Ready

Brain Cancer Clinical Trial in Orange, CA

Access cutting-edge brain cancer treatment through this clinical trial at a research site in Orange. Study-provided care at no cost to qualified participants.

Sponsored by University of California, Irvine

Quick Self-Assessment

See if you qualify for this Orange location

Preparing your pre-screening questions…

Expert Care in Orange

Access brain cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related brain cancer treatment provided free

Apply for This Orange Location

Check if you qualify for this brain cancer clinical trial in Orange, CA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Orange

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Orange site if eligible
  4. 4Begin participation

About This Brain Cancer Study in Orange

This is a Pilot clinical trial determining the safety of an active surveillance approach to local therapy in subjects with brain metastases. These are subjects who are undergoing CNS-penetrating systemic therapy.

Sponsor: University of California, Irvine

Who Can Participate

Inclusion Criteria

Patients must have histologically or cytologically confirmed metastatic non-hematologic malignancy.
Patients must have at least one new or progressive brain metastasis that has not received prior local therapy (surgery or radiation therapy).
Patients must have no active brain metastasis \>3cm in size.
Leptomeningeal disease is permitted
Patients with only non-measurable disease as defined by the RANO-BM criteria are permitted so long as the clinical determination of new or progressive disease has been made by the treating team.
Patients must have no symptoms attributable to active brain metastases.
At the time of enrollment, patients must be eligible for AND planning to begin a new line of systemic therapy with potential for CNS-efficacy. Determination of potential for CNS-efficacy will be determined based on the clinical judgement of the treating physicians. Patients must have had no prior exposure to the specific systemic therapy in question at the time of enrollment, though exposure to other medications from a similar class are acceptable at the discretion of the treating team.
Patient must be planning to defer radiation therapy to trial medical therapy regardless of enrollment on trial.
Must be age ≥ 18 years.
Patients must be willing to complete MoCA and FACT-BR assessments (refer to section 4.4.1).
Performance status: KPS performance status ≥50%.
Life expectancy of ≥3 months.
Ability to understand and willingness to sign a written informed consent document.

Exclusion Criteria

Patients who have only progressive growth of brain lesions that have previously been treated with surgery or radiation therapy.
Patients with active symptomatic brain metastases.
Patients requiring corticosteroids, anticonvulsants, or other palliative medications related to brain metastases.
Patients with conditions that exclude them from undergoing magnetic resonance imaging.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Orange?

Yes, this clinical trial (NCT07827001) has an active research site in Orange, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Brain Cancer Treatment Options in Orange, CA

If you're searching for brain cancer treatment options in Orange, CA, this clinical trial (NCT07827001) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Orange research site is actively enrolling participants for this clinical trial. You'll receive care from experienced brain cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all brain cancer clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Orange, CA