Durham, NCNCT06639607Now EnrollingIRB Ready

Brain Cancer Clinical Trial in Durham, NC

Access cutting-edge brain cancer treatment through this clinical trial at a research site in Durham. Study-provided care at no cost to qualified participants.

Sponsored by Washington University School of Medicine

Quick Self-Assessment

See if you qualify for this Durham location

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Expert Care in Durham

Access brain cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related brain cancer treatment provided free

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Check if you qualify for this brain cancer clinical trial in Durham, NC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Durham

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Durham site if eligible
  4. 4Begin participation

About This Brain Cancer Study in Durham

This is a multisite, phase I/II clinical trial in children and young adults with newly-diagnosed high-grade glioma (HGG), diffuse midline glioma (DMG) and recurrent HGG/DMG, Medulloblastoma (MB), or ependymoma (EPN) to determine the safety, immunogenicity, and efficacy of a CMV-directed peptide vaccine plus checkpoint blockade.

Sponsor: Washington University School of Medicine

Who Can Participate

Inclusion Criteria

for All Patients:
Patients must be ≥4 and ≤25 years of age (inclusive) at the time of study enrollment
Metastatic Disease: Patients with M+ disease are eligible.
Adequate bone marrow function defined as:
ANC (Absolute neutrophil count) ≥ 1000/µl.
Platelets ≥ 75,000/µl.
Hemoglobin \> 8 g/dL. (may be supported)
Adequate renal function defined as:
Creatinine clearance or radioisotope GFR ≥ 70ml/min/1.73 m\^2 OR A serum creatinine based on age/gender as listed in the protocol. Note: The threshold creatinine values in this table were derived from the Schwartz formula for estimating GFR utilizing child length and stature data published by the CDC.
Adequate liver function defined as:
Total bilirubin ≤1.5 times institutional ULN
AST(SGOT) ≤3 × institutional upper limit of normal
ALT(SGPT) ≤3 × institutional upper limit of normal
The effects of PEP-CMV and nivolumab on the developing human fetus are unknown. For this reason, female

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Durham?

Yes, this clinical trial (NCT06639607) has an active research site in Durham, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Brain Cancer Treatment Options in Durham, NC

If you're searching for brain cancer treatment options in Durham, NC, this clinical trial (NCT06639607) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Durham research site is actively enrolling participants for this clinical trial. You'll receive care from experienced brain cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all brain cancer clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Durham, NC