Boston, MANCT07132190Now EnrollingIRB Ready

Brain Metastases, Adult Clinical Trial in Boston, MA

Access cutting-edge brain metastases, adult treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Ayal A. Aizer, MD

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Expert Care in Boston

Access brain metastases, adult specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related brain metastases, adult treatment provided free

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Check if you qualify for this brain metastases, adult clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Brain Metastases, Adult Study in Boston

The goal of this study is to evaluate the feasibility and effectiveness of same-day radiation planning and treatment. The study will shorten the time interval between radiation planning (radiation mapping) and radiation treatment. The intent of this shorter time interval is to increase the likelihood that the brain metastases being treated remain fully within the high-dose radiation fields. Participants will be randomized to receive brain-directed stereotactic radiation with a 1mm margin or 0mm margin, have their simulation/radiation planning imaging on the same day that brain-directed stereotactic radiation is delivered, and have repeat simulation/radiation planning scans during the course of treatment if more than 2-3 days have elapsed since the most recent scans.

Sponsor: Ayal A. Aizer, MD

Who Can Participate

Inclusion Criteria

Participants must have a biopsy proven solid malignancy with at least one intact, residual or recurrent, intracranial lesion radiographically consistent with or pathologically proven to be a brain metastasis meeting one of the following criteria:
Growth of 1.0mm per week or more, on average, based on the two most recent brain MRIs preceding study enrollment
Abutment, to within 1.0cm, of a region of intracranial edema
Proximity (within 5.0cm) to a surgical cavity created within 30 days of enrollment
Proximity (within 5.0cm) to another source of physical displacement
Age of at least 18 years
Karnofsky performance status of at least 60
Estimated survival of at least 3-6 months in the opinion of the enrolling clinician and/or study PI
Ability to understand and the willingness to sign a written informed consent document by either ink on paper or a DF/HCC approved eConsent medium

Exclusion Criteria

Participants who cannot tolerate a brain MRI
Patients who cannot receive gadolinium
Participants with end stage renal disease
Participants with widespread, definitive leptomeningeal disease
Pregnant women are excluded from this study because of the potential deleterious effects of gadolinium on the developing fetus. Because there is an unknown but potential risk for adverse events in nursing infants, women who are breastfeeding are not eligible for this study as well

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT07132190) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Brain Metastases, Adult Treatment Options in Boston, MA

If you're searching for brain metastases, adult treatment options in Boston, MA, this clinical trial (NCT07132190) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced brain metastases, adult specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all brain metastases, adult clinical trials near you to find additional studies recruiting in your area.

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