Madison, WINCT06086704Now EnrollingIRB Ready

Breast Cancer Clinical Trial in Madison, WI

Access cutting-edge breast cancer treatment through this phase 2 clinical trial at a research site in Madison. Study-provided care at no cost to qualified participants.

Sponsored by University of Wisconsin, Madison

Quick Self-Assessment

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Expert Care in Madison

Access breast cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related breast cancer treatment provided free

Apply for This Madison Location

Check if you qualify for this breast cancer clinical trial in Madison, WI

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Madison

    Convenient for WI residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Madison site if eligible
  4. 4Begin participation

About This Breast Cancer Study in Madison

This clinical trial will investigate an estrogen-regulated parameter as an early measure of endocrine therapy response: progesterone receptor (PR) protein with a progestin-based radioligand, 18F-fluorofuranylnorprogesterone (18F-FFNP). The overall purpose of this research is to test the efficacy of 18F-FFNP PET/MRI for predicting response to presurgical endocrine therapy and to determine the quantitative reliability of 18F-FFNP breast PET/MRI in patients with newly diagnosed PR+ primary breast cancer.

Sponsor: University of Wisconsin, Madison

Who Can Participate

Inclusion Criteria

Postmenopausal status defined by either
prior bilateral oophorectomy
age greater than or equal to 60 years of age
age less than 60 years of age and amenorrheic for 12 or more months in the absence of prior chemotherapy, tamoxifen, toremifene or ovarian suppression and FSH and estradiol in the postmenopausal range per local normal range (Group 2 only)
Diagnosis of biopsy-proven invasive breast cancer measuring at least 1.0 cm in diameter by any imaging modality. Malignancy may be located within the breast, axilla (e.g. metastatic axillary lymph node), or both the breast and axilla
Biopsy-proven PR-positive invasive breast cancer
Definitive surgical excision of the primary tumor planned without neoadjuvant therapy; defined as therapy (chemotherapy, targeted therapy, radiation therapy or endocrine therapy) given to decrease the size of the tumor prior to planned surgery. (Group 2 only)

Exclusion Criteria

Inability or unwillingness to provide informed consent to the study
HER2-positive breast cancer, as defined by immunohistochemical staining 3+ OR positive by in situ hybridization (Group 2 only)
PR and Ki67 IHC slides or FFPE tissue blocks from clinical breast biopsy not available
Patients who have completed neoadjuvant chemotherapy, endocrine therapy, targeted therapy, surgical resection, or radiation for the current biopsy-proven malignancy (Group 2 only)
Patients who are planning to undergo anastrozole as standard of care neoadjuvant therapy
Patients who are currently taking aromatase inhibitors or ER antagonists (tamoxifen, raloxifene)
Patients with breast expanders
Patients who are pregnant or lactating
Patients with clinical contraindication for use of aromatase inhibitors (AI) while on study as determined by investigator (Group 2 only)
Patients with a contraindication to gadolinium-based contrast agents, including allergy or impaired renal function (per UW Health Guidelines)
Patients with a history of allergic reaction attributable to compounds of similar chemical or biologic composition to 18F-FFNP
Patients with history of allergic reaction to anastrozole (Group 2 only)
Patients in liver failure as judged by the patient's physician
Patients with standard contraindications to MRI (per UW Health Guidelines)
Patients requiring conscious sedation for imaging are not eligible; patients requiring mild, oral anxiolytics for the clinical MRI scan will be allowed to participate as long as the following criteria are met:
The patient has their own prescription for the medication
The informed consent process is conducted prior to the self-administration of the medication.
The patient comes to the research visit with a driver.
Patients unable to lie prone for 45 minutes for imaging

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Madison?

Yes, this clinical trial (NCT06086704) has an active research site in Madison, WI that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Breast Cancer Treatment Options in Madison, WI

If you're searching for breast cancer treatment options in Madison, WI, this clinical trial (NCT06086704) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Madison research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced breast cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all breast cancer clinical trials near you to find additional studies recruiting in your area.

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