NCT07778823 · Johns Hopkins University
Augmented Reality-Cardiopulmonary Resuscitation Support for Pediatric Resuscitation
(AR-CPR)
What this study is about
This study evaluates whether an augmented reality cardiopulmonary resuscitation feedback system (AR-CPR) can support health care providers in delivering high-quality chest compressions during pediatric cardiac arrest. AR-CPR provides real-time visual feedback on chest compression rate, depth, and recoil through a head-mounted augmented reality display.
View original scientific description
This study evaluates whether an augmented reality cardiopulmonary resuscitation feedback system (AR-CPR) can support health care providers in delivering high-quality chest compressions during pediatric cardiac arrest. AR-CPR provides real-time visual feedback on chest compression rate, depth, and recoil through a head-mounted augmented reality display. In this randomized, multicenter, international, simulation-based non-inferiority study, health care providers perform chest compressions during an 18-minute simulated pediatric cardiac arrest. Participants are assigned to receive either real-time feedback from AR-CPR or coaching from a trained human CPR coach. The primary objective is to determine whether the percentage of chest compressions meeting guideline targets for both rate and depth with AR-CPR is non-inferior to that achieved with human CPR coaching.
Interventions
DEVICE
AR-CPR
AR-CPR is a real-time augmented reality CPR feedback system designed to guide chest compression performance during pediatric cardiac arrest. The system uses a compression sensor containing an inertial measurement unit (IMU) and force-sensitive resistor (FSR) connected to a microcontroller. Sensor data are relayed to a Raspberry Pi 5 microcomputer running custom AR-CPR Coach software, which calculates chest compression rate, depth, and recoil. These metrics are transmitted wirelessly to a Vuzix M400 head-mounted display. The augmented reality interface provides numerical values and visual cues within the user's field of view. When performance is outside established targets, the system provides qualitative feedback and, for persistent deviations, escalates to explicit goal-directed instructions.
Primary outcome measures
Percentage of Overall Excellent CPR
Time frame: Up to 18 minutes
Percentage of chest compressions meeting the study-defined composite criterion for overall excellent CPR. This is a single composite outcome measure in which each chest compression is classified as meeting the outcome only when both compression rate and compression depth simultaneously meet American Heart Association Pediatric Advanced Life Support (AHA PALS) guideline targets. A compression must have both a rate of 100-120 compressions per minute and a depth of 5-6 cm to meet the composite outcome. If either the rate or depth is outside its target range, the compression does not meet the outcome. Rate and depth are therefore not evaluated as separate measurements for this primary outcome; they are simultaneous criteria used to determine whether each compression meets the single composite measure.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Actively credentialed pediatric emergency department or pediatric intensive care unit nurse or clinical technician at a participating study site
- Current American Heart Association (AHA) Pediatric Advanced Life Support (PALS) certification
Exclusion criteria
- Inability to physically perform chest compressions
- Need for prescription corrective lenses without having those corrective lenses available at the time of study participation
Where
- St. Petersburg, Florida
- Baltimore, Maryland
- New York, New York
- Philadelphia, Pennsylvania
- Providence, Rhode Island
- Dallas, Texas
- Houston, Texas
Collaborators
The Hospital for Sick Children, Columbia University, Brown University, Children's Hospital of Philadelphia, Johns Hopkins All Children's Hospital, Children's Medical Center Dallas, Baylor College of Medicine, Agency for Healthcare Research and Quality (AHRQ)
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Frequently asked questions
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Data: ClinicalTrials.gov · synced Aug 21, 2026 · Source of record for eligibility and locations