Baltimore, MDNCT07734870Now EnrollingIRB Ready

Central Centrifugal Cicatricial Alopecia (CCCA) Clinical Trial in Baltimore, MD

Access cutting-edge central centrifugal cicatricial alopecia (ccca) treatment through this phase 2 clinical trial at a research site in Baltimore. Study-provided care at no cost to qualified participants.

Sponsored by Johns Hopkins University

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Expert Care in Baltimore

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related central centrifugal cicatricial alopecia (ccca) treatment provided free

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Why Participate?

  • No-Cost Study Care

  • Local to Baltimore

    Convenient for MD residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Baltimore site if eligible
  4. 4Begin participation

About This Central Centrifugal Cicatricial Alopecia (CCCA) Study in Baltimore

The goal of this pilot clinical trial is to learn if tirzepatide can treat active central centrifugal cicatricial alopecia (CCCA), a type of permanent scarring hair loss, in adults. The main questions it aims to answer are: * Does tirzepatide improve the symptoms and signs of active CCCA? * Does tirzepatide change the activity of genes in the scalp, especially genes related to scarring? * Does tirzepatide promote hair regrowth? Participants will: * Inject tirzepatide once a week for 12 months. * Visit the clinic for scalp examinations, photographs, and other health assessments. * Have scalp biopsies at the beginning of the study and after 6 months of treatment. * Have blood tests and other safety monitoring during the study. There is no separate comparison group. Researchers will compare each participant's results during treatment with the participant's results at the beginning of the study.

Sponsor: Johns Hopkins University

Who Can Participate

Inclusion Criteria

Age 18 to 80 years.
Clinical and/or biopsy-confirmed diagnosis of central centrifugal cicatricial alopecia (CCCA).
Active CCCA, defined as a C-CAT disease activity score greater than 1.
No treatment for CCCA during the 6 weeks before enrollment.
Able and willing to complete the study and follow all study procedures.
Managed by a Johns Hopkins dermatologist throughout the study.

Exclusion Criteria

Currently taking an oral or systemic blood glucose-lowering medication.
Currently taking another medication for weight loss.
Hemoglobin A1C below 5.4%.
Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) score below 2.
Body mass index below 19 kg/m².
Pregnant, breastfeeding, or planning a pregnancy.
Personal or family history of medullary thyroid cancer.
Personal or family history of multiple endocrine neoplasia type 2.
History of chronic kidney disease.
History of pancreatitis.
History of diabetic retinopathy.
Severe gastrointestinal disease.
Recent or planned major surgery.
Type 1 diabetes.
Any other contraindication to tirzepatide.
History of keloids or hypertrophic scarring.
History of poor wound healing.
History of a blood-clotting disorder.
Allergy to lidocaine or epinephrine.
Known sensitivity to local numbing medication.
Any significant medical condition that the investigator believes would make participation unsafe or prevent completion of the study.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Baltimore?

Yes, this clinical trial (NCT07734870) has an active research site in Baltimore, MD that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Central Centrifugal Cicatricial Alopecia (CCCA) Treatment Options in Baltimore, MD

If you're searching for central centrifugal cicatricial alopecia (ccca) treatment options in Baltimore, MD, this clinical trial (NCT07734870) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Baltimore research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced central centrifugal cicatricial alopecia (ccca) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all central centrifugal cicatricial alopecia (ccca) clinical trials near you to find additional studies recruiting in your area.

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