Rochester, MNNCT05411523Now EnrollingIRB Ready

Chemotherapy-Induced Peripheral Neuropathy Clinical Trial in Rochester, MN

Access cutting-edge chemotherapy-induced peripheral neuropathy treatment through this clinical trial at a research site in Rochester. Study-provided care at no cost to qualified participants.

Sponsored by Mayo Clinic

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Expert Care in Rochester

Access chemotherapy-induced peripheral neuropathy specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related chemotherapy-induced peripheral neuropathy treatment provided free

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Check if you qualify for this chemotherapy-induced peripheral neuropathy clinical trial in Rochester, MN

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Rochester

    Convenient for MN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Rochester site if eligible
  4. 4Begin participation

About This Chemotherapy-Induced Peripheral Neuropathy Study in Rochester

This study examines how spinal cord stimulation (SCS) affects pain level and quality of life in patients experiencing chemotherapy-induced peripheral neuropathy (CIPN). CIPN is a nerve problem and one of the potential side effects of chemotherapy that causes pain, numbness, tingling, swelling, or muscle weakness in different parts of the body. CIPN usually begins in the hands or feet and gets worse over time. SCS is a type of therapy that has proven to be effective in treating numerous non-malignant pain disorders including failed back surgery syndrome, refractory angina, limb ischemia, complex regional pain syndrome, and diabetic peripheral neuropathy. SCS may also be useful in patients with CIPN. This study evaluates how SCS affects pain and quality of life in patients undergoing spinal cord stimulation for CIPN.

Sponsor: Mayo Clinic

Who Can Participate

Inclusion Criteria

Adult patients greater than or equal to 18 years of age who have been clinically diagnosed with CIPN for greater than six months after stopping chemotherapy
Average pain intensity \>= 5 on 11-point numeric rating scale (NRS) in the lower extremities at enrollment
Failed conventional medication management with at least two neuropathic pain medications
Have electrophysiological evidence of length-dependent peripheral neuropathy
Underwent a 10-kHz spinal cord stimulator trial for a primary indication of CIPN and reported a successful trial of at least 75% reduction in pain intensity
Have stable neurological status
Be on a stable analgesic regimen
Be an appropriate candidate for surgical procedures required in this study
Be able to read and understand English-written questionnaires and sign an informed consent form in English
Be willing and capable of giving informed consent
Be willing and able to complete study-related requirements, procedures, and visits

Exclusion Criteria

Patient refusal to be included in study
Presence of lower limb mononeuropathy
History of lower limb amputation or ulceration
Presence of another painful condition that is unrelated to CIPN and that is not intended to be treated in this study
Body mass index (BMI) \>= 40
Omeprazole (OME) \> 120 mg
Progressive neurological disease (multiple sclerosis, chronic inflammatory demyelinating polyneuropathy, rapidly progressive arachnoiditis, brain or spinal cord tumor, central deafferentation syndrome, complex regional pain syndrome, acute herniating disc, severe spinal stenosis)
Certain comorbidities: coagulation/bleeding disorders, diminished capacity from cardiac/pulmonary disease
Obtaining another interventional procedure unrelated to SCS to treat limb pain
Have ongoing metastatic malignant neoplasm or untreated local malignant neoplasm. Included patients must be deemed as in remission per discretion of treating oncologist
Have a life expectancy of less than one year
Have untreated addiction or dependency to medications, alcohol, or illicit drugs
Have active, disruptive, and/or unstable psychological or psychiatric disorder

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Rochester?

Yes, this clinical trial (NCT05411523) has an active research site in Rochester, MN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Chemotherapy-Induced Peripheral Neuropathy Treatment Options in Rochester, MN

If you're searching for chemotherapy-induced peripheral neuropathy treatment options in Rochester, MN, this clinical trial (NCT05411523) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Rochester research site is actively enrolling participants for this clinical trial. You'll receive care from experienced chemotherapy-induced peripheral neuropathy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all chemotherapy-induced peripheral neuropathy clinical trials near you to find additional studies recruiting in your area.

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