Cleveland, OHNCT07219472Now EnrollingIRB Ready

Chemotherapy-induced Peripheral Neuropathy Clinical Trial in Cleveland, OH

Access cutting-edge chemotherapy-induced peripheral neuropathy treatment through this clinical trial at a research site in Cleveland. Study-provided care at no cost to qualified participants.

Sponsored by Case Comprehensive Cancer Center

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Expert Care in Cleveland

Access chemotherapy-induced peripheral neuropathy specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related chemotherapy-induced peripheral neuropathy treatment provided free

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Check if you qualify for this chemotherapy-induced peripheral neuropathy clinical trial in Cleveland, OH

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Cleveland

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Cleveland site if eligible
  4. 4Begin participation

About This Chemotherapy-induced Peripheral Neuropathy Study in Cleveland

This research study is for people who have a condition called chemotherapy-induced peripheral neuropathy (CIPN). This condition develops as a result of receiving medication(s) to treat cancer, particularly chemotherapy. CIPN is characterized by pain, numbness, tingling or burning sensations, typically in the hands and feet of people. These symptoms can lead to physical suffering, limited ability to perform daily activities, and low quality of life. One of the ways to treat CIPN is using a device called Scrambler Therapy. Scrambler Therapy was approved by the Food and Drug Administration (FDA) in 2009 as a treatment for CIPN. The treatment involves electrical signals passing through wires attached to parts of the body via adhesive tabs near where symptoms of CIPN are experienced. A standard treatment course consists of 10 daily sessions lasting about one hour each. The purpose of this study is to determine the effect of a 10-day course of Scrambler Therapy on symptoms of chemotherapy-induced peripheral neuropathy, day-to-day activities, overall quality of life, and use of pain medications. Participants will be randomly assigned to one of two groups. One group will receive Scrambler Therapy. The other group will not receive it. Participants will not know which group they were in until after treatment has completed. Participants in the group who did not receive Scrambler Therapy will have the opportunity to receive it after one month. Participants will be in this research study about 12 to 14 months.

Sponsor: Case Comprehensive Cancer Center

Who Can Participate

Inclusion Criteria

Adults with CIPN-related pain for at least three months duration, and for which the participant wants intervention
At least three months from the last dose of neurotoxic cancer-directed drug
No plan (at the time of study enrollment) for additional neurotoxic cancer-directed therapies for at least five months after trial enrollment
Pain rated ≥ four out of 10 in severity (0-10 pain scale) during the seven days prior to enrollment
\> six-month life expectancy
Able to complete questionnaires by themselves or with assistance
Able to provide informed written consent
ECOG Performance Status score ≥ two

Exclusion Criteria

Pregnant or nursing
An operational implanted drug delivery system, implanted electronic medical device, life supporting medical device, and/or medical monitoring device
History of myocardial infarction or ischemic heart disease within six months of trial enrollment
History of epilepsy, brain damage resulting in seizure activity, or use of anticonvulsants for seizure
Skin conditions such as open sores that will prevent proper application of electrodes
Unwillingness or inability to wean and discontinue gabapentin or pregabalin prior to the start of ST
History of symptomatic peripheral neuropathy prior to receiving neurotoxic chemotherapy
Prior treatment with Scrambler Therapy

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cleveland?

Yes, this clinical trial (NCT07219472) has an active research site in Cleveland, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Chemotherapy-induced Peripheral Neuropathy Treatment Options in Cleveland, OH

If you're searching for chemotherapy-induced peripheral neuropathy treatment options in Cleveland, OH, this clinical trial (NCT07219472) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cleveland research site is actively enrolling participants for this clinical trial. You'll receive care from experienced chemotherapy-induced peripheral neuropathy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all chemotherapy-induced peripheral neuropathy clinical trials near you to find additional studies recruiting in your area.

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