Denton, TXNCT05727176Now EnrollingIRB Ready

Cholangiocarcinoma Clinical Trial in Denton, TX

Access cutting-edge cholangiocarcinoma treatment through this phase 2 clinical trial at a research site in Denton. Study-provided care at no cost to qualified participants.

Sponsored by Taiho Oncology, Inc.

Quick Self-Assessment

See if you qualify for this Denton location

Preparing your pre-screening questions…

Expert Care in Denton

Access cholangiocarcinoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related cholangiocarcinoma treatment provided free

Apply for This Denton Location

Check if you qualify for this cholangiocarcinoma clinical trial in Denton, TX

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Denton

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Denton site if eligible
  4. 4Begin participation

About This Cholangiocarcinoma Study in Denton

This is an open-label, multinational, randomized Phase 2 study confirming the clinical benefit of 20 mg futibatinib and evaluating the safety and efficacy of 16 mg futibatinib in previously treated CCA harboring FGFR2 gene fusions and other rearrangements.

Sponsor: Taiho Oncology, Inc.

Who Can Participate

Inclusion Criteria

Histologically or cytologically confirmed, locally advanced, metastatic, or unresectable intrahepatic of extrahepatic Cholangiocarcinoma.
Documented evidence of FGFR2 gene fusions or other FGFR2 rearrangement
Received at least one prior systemic gemcitabine and platinum-based regimen for CCA
Documentation of radiographic disease progression on the most recent prior therapy
Measurable disease
performance status 0 or 1
Adequate organ function

Exclusion Criteria

History or current evidence of calcium and phosphate homeostasis disorder
Current evidence of clinically significant retinal disorder
Treatment with any of the following within the specified time frame prior to the first dose of futibatinib:
Major surgery within the previous 4 weeks (the surgical incision should be fully healed prior to the first dose of futibatinib) and radiotherapy for extended field within 4 weeks or limited field radiotherapy within 2 weeks
Patients with locoregional therapy, eg, transarterial chemoembolization (TACE), selective internal radiotherapy (SIRT) or ablation within 4 weeks
Any non investigational anticancer therapy within 3 weeks or have not recovered from side effects of such therapy prior to futibatinib. Endocrine therapy is allowed for patients with breast or prostate cancer
Targeted therapy or immunotherapy within 3 weeks or within 5 half lives Any investigational agent received within 5 half-lives of the drug or 4 weeks, whichever is shorter.
Patients with prior FGFR-directed therapy
A serious illness or medical condition(s) including (but not limited to) the following:
Known brain metastasis (not including primary brain tumors) unless patient is clinically stable for ≥1 month
Known acute systemic infection
Myocardial infarction, severe/unstable angina, symptomatic congestive heart failure (New York Heart Association \[NYHA\] Class III or IV New York Heart Association \[NYHA\] Classification) within the previous 2 months; if \>2 months, cardiac function must be within normal limits and the patient must be free of cardiac-related symptoms
Significant gastrointestinal disorder(s) that could interfere with the absorption of futibatinib.
Other severe acute or chronic medical or psychiatric condition or laboratory abnormality that in the judgment of the Investigator would make the patient inappropriate for entry into this study.
Known additional malignancy that is progressing or requires active treatment, with the exception of patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or antitumor assessment of the investigational regimen. Exceptions must be discussed with the Sponsor prior to patient enrollment.
Pregnant or lactating female.
Known hypersensitivity or severe reaction to futibatinib or its excipients.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Denton?

Yes, this clinical trial (NCT05727176) has an active research site in Denton, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Cholangiocarcinoma Treatment Options in Denton, TX

If you're searching for cholangiocarcinoma treatment options in Denton, TX, this clinical trial (NCT05727176) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Denton research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced cholangiocarcinoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all cholangiocarcinoma clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Denton, TX