Ann Arbor, MINCT06419439Now EnrollingIRB Ready

Chronic Low Back Pain Clinical Trial in Ann Arbor, MI

Access cutting-edge chronic low back pain treatment through this phase 2 clinical trial at a research site in Ann Arbor. Study-provided care at no cost to qualified participants.

Sponsored by VA Office of Research and Development

Quick Self-Assessment

See if you qualify for this Ann Arbor location

Preparing your pre-screening questions…

Expert Care in Ann Arbor

Access chronic low back pain specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related chronic low back pain treatment provided free

Apply for This Ann Arbor Location

Check if you qualify for this chronic low back pain clinical trial in Ann Arbor, MI

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Ann Arbor

    Convenient for MI residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Ann Arbor site if eligible
  4. 4Begin participation

About This Chronic Low Back Pain Study in Ann Arbor

This is a pilot study to evaluate the feasibility, acceptability, and safety of ketamine infusions followed by a brief behavioral intervention in Veterans with chronic low back pain and depression.

Sponsor: VA Office of Research and Development

Who Can Participate

Inclusion Criteria

Veterans with self-report of moderate to severe, high impact chronic low back pain (defined as 4/10 in severity via NRS, present 3 months on most days) and associated pain interference (defined as T-score 60 on the PROMIS Pain Interference measure), and current significant depressive symptoms (defined as a score 11 on the Quick Inventory of Depressive Symptoms - Self Report (QIDS-SR).
Medically stable (no hospitalizations in the past month lasting 3 days).
No changes in pain or depression medication regimen in 4 weeks.
No planned surgery, injections, hospitalizations, or other new interventions for back pain (except for physical therapy or exercise) or depression during the next four months (study duration).
Participants must have an adult who can drive them home after the ketamine treatments.

Exclusion Criteria

Inability to speak English due to the narrative intervention being conducted in English.
Inability or unwillingness to provide written informed consent (e.g. current delirium).
Current psychotic symptoms, or history of schizophrenia, schizoaffective disorder, and other psychotic disorder.
Currently participating in another clinical trial for pain or depression.
Current uncontrolled hypertension (defined as systolic blood pressure \>160 mmHg and/or diastolic blood pressure \>100 mmHg).
Known elevated intracranial pressure, cerebral arterial aneurysm, or elevated intraocular pressure.
History of cirrhosis or unstable cardiac condition (e.g., decompensated congestive heart failure).
Any of the following lab values \>2x upper limit of normal: alanine transaminase (ALT), aspartate transferase (AST), direct bilirubin, alkaline phosphatase, creatinine; thyroid stimulating hormone (TSH) \<2x lower limit of normal or \>2x upper limit of normal.
Positive urine pregnancy test or lack of birth control method in Veterans of childbearing potential.
Known hypersensitivity to any excipient in the ketamine injection formulation.
Previously experienced serious adverse effects with ketamine.
On day of ketamine infusions, a urine drug screen positive for non-prescribed substances(s) (except cannabis) will exclude a participant from receiving ketamine
Current or previous abuse of ketamine.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Ann Arbor?

Yes, this clinical trial (NCT06419439) has an active research site in Ann Arbor, MI that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Chronic Low Back Pain Treatment Options in Ann Arbor, MI

If you're searching for chronic low back pain treatment options in Ann Arbor, MI, this clinical trial (NCT06419439) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Ann Arbor research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced chronic low back pain specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all chronic low back pain clinical trials near you to find additional studies recruiting in your area.

More Interstitial Cystitis Trials in Ann Arbor, MI

See all interstitial cystitis clinical trials recruiting in Ann Arbor — not just this study.

Browse Interstitial Cystitis Trials in Ann Arbor →

Browse More Trials by Condition

Interstitial Cystitis TrialsBack Pain TrialsAll Conditions →

Ready to Join in Ann Arbor?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Ann Arbor, MI