Winston Salem, NCNCT07024706Now EnrollingIRB Ready

Chronic Lymphocytic Leukemia (CLL) Clinical Trial in Winston Salem, NC

Access cutting-edge chronic lymphocytic leukemia (cll) treatment through this clinical trial at a research site in Winston Salem. Study-provided care at no cost to qualified participants.

Sponsored by AstraZeneca

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Expert Care in Winston Salem

Access chronic lymphocytic leukemia (cll) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related chronic lymphocytic leukemia (cll) treatment provided free

Apply for This Winston Salem Location

Check if you qualify for this chronic lymphocytic leukemia (cll) clinical trial in Winston Salem, NC

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Why Participate?

  • No-Cost Study Care

  • Local to Winston Salem

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Winston Salem site if eligible
  4. 4Begin participation

About This Chronic Lymphocytic Leukemia (CLL) Study in Winston Salem

This study will evaluate the efficacy and safety of finite-duration acalabrutinib plus venetoclax therapy in patients with relapsed CLL or SLL, and have previously responded to first line (1L) cBTKi + BCL2i therapy (± obinutuzumab) and maintained a response for at least two years post-treatment.

Sponsor: AstraZeneca

Who Can Participate

Inclusion Criteria

Participant must be ≥ 18 years at the time of signing informed consent.
Diagnosis of CLL/SLL according to iwCLL guidelines 2018 (Hallek et al. 2018)
Participants must have received first line treatment with fixed duration covalent BTKi plus BCL2i therapy (± obinutuzumab) with a response ≥ PR (i.e., CR, CRi, nPR, or PR) with a minimum of 2 years since the end of the prior 1L treatment.
The following data must be available or at least the appropriate samples drawn/acquired prior to dosing:
IGHV (mutated vs. unmutated)
del(17p) (present or absent)
TP53 mutation (present or absent)
ECOG performance status 0, 1 or 2
Adequate organ and bone marrow (BM) function. Main

Exclusion Criteria

Any evidence of diseases that, in the investigator's opinion, makes it undesirable for patient to participate in the study.
Significant cardiovascular or cerebrovascular disease.
Active bleeding or history of bleeding diathesis (e.g., hemophilia or von Willebrand disease).
Child-Pugh B/C liver cirrhosis.
History of prior or current malignancy.
HIV positive
History of progressive multifocal leukoencephalopathy (PML).
Active hepatitis B or C infection:
Corticosteroid use \> 20 mg within 1 week before the first dose of study intervention.
History of hypersensitivity or anaphylaxis to study intervention(s).
Requires treatment with a strong CYP3A4 inhibitor/inducer.
Requires or receiving anticoagulation with warfarin or equivalent vitamin K antagonists.
Major surgical procedure within 30 days of the first dose of study intervention.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Winston Salem?

Yes, this clinical trial (NCT07024706) has an active research site in Winston Salem, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Chronic Lymphocytic Leukemia (CLL) Treatment Options in Winston Salem, NC

If you're searching for chronic lymphocytic leukemia (cll) treatment options in Winston Salem, NC, this clinical trial (NCT07024706) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Winston Salem research site is actively enrolling participants for this clinical trial. You'll receive care from experienced chronic lymphocytic leukemia (cll) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all chronic lymphocytic leukemia (cll) clinical trials near you to find additional studies recruiting in your area.

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