Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Chronic Lymphocytic Leukemia Clinical Trials
Chronic Lymphocytic Leukemia clinical trials are recruiting across 143 cities. Here are the cities with the most active studies:
Chronic Lymphocytic Leukemia Trial Phases
44 research organizations are sponsoring chronic lymphocytic leukemia trials.
About Chronic Lymphocytic Leukemia
Chronic lymphocytic leukemia (CLL) is a slow-growing cancer of the blood and bone marrow that affects B lymphocytes. It is the most common type of adult leukemia. Treatment options include targeted therapies, chemotherapy, and immunotherapy.
Clinical trials are advancing new treatments for chronic lymphocytic leukemia. Currently, 82 studies are recruiting a combined 17,854 participants across the United States. Research is being conducted by 44 organizations including Dana-Farber Cancer Institute, Merck Sharp & Dohme LLC, National Heart, Lung, and Blood Institute (NHLBI) and 41 others.
2026 Chronic Lymphocytic Leukemia Research Landscape
As of July 2026, the chronic lymphocytic leukemia clinical trial landscape includes 82 actively recruiting studies across 143 cities in the United States. These studies are collectively seeking 17,854 participants, with an average enrollment target of 218 per study.
The research spans multiple phases of development: 37 studies are in PHASE2, 17 studies are in PHASE1, 15 studies are in PHASE3, 3 studies are in PHASE4, 1 study is in NA, 1 study is in EARLY_PHASE1. The presence of Phase 3 trials indicates that some chronic lymphocytic leukemia treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 44 different organizations, including Dana-Farber Cancer Institute, Merck Sharp & Dohme LLC, National Heart, Lung, and Blood Institute (NHLBI), Loxo Oncology, Inc., Janssen Research & Development, LLC, and 39 others. The large number of sponsors reflects significant research interest and investment in chronic lymphocytic leukemia treatment advancement.
Geographically, chronic lymphocytic leukemia trials are most concentrated in Boston, Massachusetts (16 trials); Columbus, Ohio (14 trials); Bethesda, Maryland (11 trials); Duarte, California (10 trials); Rochester, Minnesota (8 trials) and 7 other cities.
Featured Chronic Lymphocytic Leukemia Studies
Highlighted recruiting studies for chronic lymphocytic leukemia, selected by enrollment size and research scope.
Understanding Chronic Lymphocytic Leukemia
The purpose of this study is to collect human Chronic Lymphocytic Leukemia tissue samples and medical information, in order to find out more about the causes and biology of chronic lymphocytic leukemia.
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
The goal of this study is to evaluate nemtabrutinib compared with investigator's choice of ibrutinib or acalabrutinib in participants with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) who have not received any prior therapy. The primary hypotheses are that (1) nemtabrutinib is non-inferior to ibrutinib or acalabrutinib with respect to objective response rate (ORR) per Intern...
Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)
Background The development of new technologies now allow scientists to investigate the molecular basis and clinical manifestations of monoclonal B cell lymphocytosis (MBL), chronic lymphocytic leukemia(CLL)/small lymphocytic lymphoma (SLL), lymphoplasmacytic lymphoma (LPL)/Waldenstrom macroglobulinemia (WM), and splenic marginal zone lymphoma (SMZL). Applying these methods in a natural history st...
Frequently Asked Questions About Chronic Lymphocytic Leukemia Clinical Trials
Are there chronic lymphocytic leukemia clinical trials near me?
Yes, there are 82 chronic lymphocytic leukemia clinical trials currently recruiting across 143+ cities in the United States, including Boston, Massachusetts; Columbus, Ohio; Bethesda, Maryland. Browse the studies above to find one at a location convenient for you.
How do I join a chronic lymphocytic leukemia clinical trial?
To join a chronic lymphocytic leukemia clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are chronic lymphocytic leukemia clinical trials free?
Yes, participation in chronic lymphocytic leukemia clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of chronic lymphocytic leukemia treatments are being studied?
Current chronic lymphocytic leukemia clinical trials are testing a range of approaches across PHASE2 (37 studies), PHASE1 (17 studies), PHASE3 (15 studies), PHASE4 (3 studies), NA (1 study), EARLY_PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 44 research organizations.
Is it safe to participate in chronic lymphocytic leukemia clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 15, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 15, 2026 · Data from ClinicalTrials.gov