Ann Arbor, MINCT05769348Now EnrollingIRB Ready

Chronic Migraine Clinical Trial in Ann Arbor, MI

Access cutting-edge chronic migraine treatment through this clinical trial at a research site in Ann Arbor. Study-provided care at no cost to qualified participants.

Sponsored by University of Michigan

Quick Self-Assessment

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Expert Care in Ann Arbor

Access chronic migraine specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related chronic migraine treatment provided free

Apply for This Ann Arbor Location

Check if you qualify for this chronic migraine clinical trial in Ann Arbor, MI

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Ann Arbor

    Convenient for MI residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Ann Arbor site if eligible
  4. 4Begin participation

About This Chronic Migraine Study in Ann Arbor

This study investigates whether unilateral and bilateral non-invasive brain stimulation, given for 20 minutes/once per day for twenty days (M-F) can reduce migraine pain. Fourty patients will receive treatment (20 unilateral treatment, and 20 bilateral treatment), while twenty will receive a "sham" procedure. Another 20 Episodic Migraine patients will be recruited for the observational aim of the study which does not include brain stimulation.

Sponsor: University of Michigan

Who Can Participate

Inclusion Criteria

Male or female, aged 18 to 65 (inclusive)
Patients must have Episodic migraines that started before the age of 50, and currently experience:
Chronic migraine (ICHD-3-beta), headache occurring on 15 days/month for more than six months, which, on at least eight days/month, has the features of a migraine headache.
Episodic migraine (low frequency), specifically those with headache occurring less than 8 days/month.
Willing to limit the introduction of new treatments and medications during the study period.

Exclusion Criteria

Significantly greater pain in body sites other than the head
Active, untreated major concurrent systemic illness other than migraine
Medical conditions that can impair health status independent of migraine (including cardiopulmonary disorders, malignancy, uncontrolled endocrine or allergies)
Systemic rheumatic disorders (i.e., rheumatoid arthritis, systemic lupus erythematosus, gout, and fibromyalgia);
History or current evidence of a psychotic disorder (e.g., bipolar disorder, schizophrenia) or severe major depression, as evidenced by Beck Depression score of \>30\
History of neurological disorder (e.g., epilepsy, stroke, neuropathy, neuropathic pain)
Medication overuse headache (ICHD-3), regular intake for ≥10 days per month of ergotamine, triptans, combination analgesics, or any combination thereof OR ≥15 days per month of simple analgesics (acetaminophen, aspirin, NSAID), for more than 3 months
Current use of opioid or dopaminergic drugs (or use within the last 3 months) or substance abuse (self-reported)
Drug test positive for opioid or recreational drug (e.g., cannabis) at the time of the PET scan visits
Allergic response to study radiotracers or chemically related drugs
Excluded by MRI Center or PET Center safety screening checklist (as administered by study staff)
Pregnant or lactating (negative urine pregnancy test must be available before any PET procedures are initiated)
Prior use of tDCS

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Ann Arbor?

Yes, this clinical trial (NCT05769348) has an active research site in Ann Arbor, MI that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Chronic Migraine Treatment Options in Ann Arbor, MI

If you're searching for chronic migraine treatment options in Ann Arbor, MI, this clinical trial (NCT05769348) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Ann Arbor research site is actively enrolling participants for this clinical trial. You'll receive care from experienced chronic migraine specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all chronic migraine clinical trials near you to find additional studies recruiting in your area.

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