Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Migraine Clinical Trials
Migraine clinical trials are recruiting across 128 cities. Here are the cities with the most active studies:
Migraine Trial Phases
38 research organizations are sponsoring migraine trials.
About Migraine
Migraine is a neurological condition characterized by intense, debilitating headaches often accompanied by nausea, light sensitivity, and visual disturbances. It affects about 1 billion people globally and is a leading cause of disability. Treatments include preventive medications, acute therapies, and newer CGRP-targeting drugs.
Clinical trials are advancing new treatments for migraine. Currently, 63 studies are recruiting a combined 35,911 participants across the United States. Research is being conducted by 38 organizations including Association of Migraine Disorders, Amgen, Pfizer and 35 others.
2026 Migraine Research Landscape
As of September 2026, the migraine clinical trial landscape includes 63 actively recruiting studies across 128 cities in the United States. These studies are collectively seeking 35,911 participants, with an average enrollment target of 570 per study.
The research spans multiple phases of development: 20 studies are in NA, 16 studies are in PHASE3, 7 studies are in PHASE4, 6 studies are in PHASE2, 2 studies are in EARLY_PHASE1, 1 study is in PHASE1. The presence of Phase 3 trials indicates that some migraine treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 38 different organizations, including Association of Migraine Disorders, Amgen, Pfizer, AbbVie, Kallyope Inc., and 33 others. The large number of sponsors reflects significant research interest and investment in migraine treatment advancement.
Geographically, migraine trials are most concentrated in Little Rock, Arkansas (9 trials); Los Angeles, California (8 trials); Phoenix, Arizona (7 trials); Stamford, Connecticut (7 trials); Gulf Breeze, Florida (7 trials) and 7 other cities.
Featured Migraine Studies
Highlighted recruiting studies for migraine, selected by enrollment size and research scope.
Headache Ear Auditory Dizziness Sinus (HEADS) Registry
The Headache, Ear, Auditory, Dizziness, Sinus (HEADS) Registry is a study over time of individuals living in the United States who experience sinus, vestibular, auditory, and headache symptoms. Through an online portal, participants are asked questions about their symptoms, how they have affected their lives, and how effectively they have managed them. This information is then used to better under...
Aimovig Pregnancy Exposure Registry
The primary objective of this study is to estimate the proportion of major congenital malformations in infants of women with migraine exposed to erenumab-aooe during pregnancy compared to infants of women with migraine unexposed to erenumeb-aooe.
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in children and adolescents.
Frequently Asked Questions About Migraine Clinical Trials
Are there migraine clinical trials near me?
Yes, there are 63 migraine clinical trials currently recruiting across 128+ cities in the United States, including Little Rock, Arkansas; Los Angeles, California; Phoenix, Arizona. Browse the studies above to find one at a location convenient for you.
How do I join a migraine clinical trial?
To join a migraine clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are migraine clinical trials free?
Yes, participation in migraine clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of migraine treatments are being studied?
Current migraine clinical trials are testing a range of approaches across NA (20 studies), PHASE3 (16 studies), PHASE4 (7 studies), PHASE2 (6 studies), EARLY_PHASE1 (2 studies), PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 38 research organizations.
Is it safe to participate in migraine clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated September 2, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated September 2, 2026 · Data from ClinicalTrials.gov