Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Traumatic Brain Injury Clinical Trials
Traumatic Brain Injury clinical trials are recruiting across 81 cities. Here are the cities with the most active studies:
Traumatic Brain Injury Trial Phases
72 research organizations are sponsoring traumatic brain injury trials.
About Traumatic Brain Injury
Traumatic brain injury (TBI) results from a violent blow or jolt to the head or body that disrupts normal brain function. Effects can range from mild concussions to severe cognitive impairment. Treatment depends on severity and may include rehabilitation, medication, and surgery.
Clinical trials are advancing new treatments for traumatic brain injury. Currently, 100 studies are recruiting a combined 38,215 participants across the United States. Research is being conducted by 72 organizations including University of Minnesota, Hoffmann-La Roche, University of Maryland, Baltimore and 69 others.
2026 Traumatic Brain Injury Research Landscape
As of July 2026, the traumatic brain injury clinical trial landscape includes 100 actively recruiting studies across 81 cities in the United States. These studies are collectively seeking 38,215 participants, with an average enrollment target of 382 per study.
The research spans multiple phases of development: 56 studies are in NA, 11 studies are in PHASE2, 5 studies are in PHASE3, 5 studies are in PHASE1, 2 studies are in PHASE4, 1 study is in EARLY_PHASE1. The presence of Phase 3 trials indicates that some traumatic brain injury treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 72 different organizations, including University of Minnesota, Hoffmann-La Roche, University of Maryland, Baltimore, Ohio State University, Wake Forest University Health Sciences, and 67 others. The large number of sponsors reflects significant research interest and investment in traumatic brain injury treatment advancement.
Geographically, traumatic brain injury trials are most concentrated in San Diego, California (7 trials); Minneapolis, Minnesota (6 trials); Cincinnati, Ohio (6 trials); Pittsburgh, Pennsylvania (6 trials); Philadelphia, Pennsylvania (5 trials) and 7 other cities.
Featured Traumatic Brain Injury Studies
Highlighted recruiting studies for traumatic brain injury, selected by enrollment size and research scope.
Evaluation of the SCALED (SCaling AcceptabLE cDs)
This project will adapt a currently deployed Clinical Decision Support (CDS) system to deliver a VTE prevention guideline for adult patients with traumatic brain injury (TBI). We believe this is an ideal PCOR use case given PCORI's continued effort to combat VTE in trauma and our experience previously implementing this guideline. The Our overall goal is to successfully scale, evaluate, and maintai...
A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury
The study is intended to cover two purposes: first, to develop a blood-based biomarker test for aiding the diagnosis of traumatic brain injury (TBI) in adult participants and for prognosis of outcome of TBI (CLIN12.1); and second, for monitoring the development of secondary events in adult participants diagnosed with TBI (CLIN12.2).
Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury
This study will look to validate predictive algorithms developed in a previous study where we collected relevant data from trauma registry and after using advanced signal-processing and machine-learning, determined prediction scores regarding neuroworsening and other outcomes following traumatic brain injury.
Frequently Asked Questions About Traumatic Brain Injury Clinical Trials
Are there traumatic brain injury clinical trials near me?
Yes, there are 100 traumatic brain injury clinical trials currently recruiting across 81+ cities in the United States, including San Diego, California; Minneapolis, Minnesota; Cincinnati, Ohio. Browse the studies above to find one at a location convenient for you.
How do I join a traumatic brain injury clinical trial?
To join a traumatic brain injury clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are traumatic brain injury clinical trials free?
Yes, participation in traumatic brain injury clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of traumatic brain injury treatments are being studied?
Current traumatic brain injury clinical trials are testing a range of approaches across NA (56 studies), PHASE2 (11 studies), PHASE3 (5 studies), PHASE1 (5 studies), PHASE4 (2 studies), EARLY_PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 72 research organizations.
Is it safe to participate in traumatic brain injury clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov