Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Huntingtons Disease Clinical Trials
Huntingtons Disease clinical trials are recruiting across 94 cities. Here are the cities with the most active studies:
Huntingtons Disease Trial Phases
66 research organizations are sponsoring huntingtons disease trials.
About Huntingtons Disease
Huntington's disease is an inherited condition that causes progressive degeneration of nerve cells in the brain, affecting movement, cognition, and behavior. It is caused by a mutation in the HTT gene. Current treatments manage symptoms, while gene-silencing therapies are being studied.
Clinical trials are advancing new treatments for huntingtons disease. Currently, 78 studies are recruiting a combined 51,403 participants across the United States. Research is being conducted by 66 organizations including CHDI Foundation, Inc., University College, London, Incyte Corporation and 63 others.
2026 Huntingtons Disease Research Landscape
As of July 2026, the huntingtons disease clinical trial landscape includes 78 actively recruiting studies across 94 cities in the United States. These studies are collectively seeking 51,403 participants, with an average enrollment target of 659 per study.
The research spans multiple phases of development: 31 studies are in NA, 11 studies are in PHASE4, 10 studies are in PHASE2, 6 studies are in PHASE1, 3 studies are in PHASE3. The presence of Phase 3 trials indicates that some huntingtons disease treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 66 different organizations, including CHDI Foundation, Inc., University College, London, Incyte Corporation, Brigham and Women's Hospital, HELP for NOWS Consortium, and 61 others. The large number of sponsors reflects significant research interest and investment in huntingtons disease treatment advancement.
Geographically, huntingtons disease trials are most concentrated in Baltimore, Maryland (11 trials); Birmingham, Alabama (8 trials); Pittsburgh, Pennsylvania (8 trials); Boston, Massachusetts (7 trials); Los Angeles, California (6 trials) and 7 other cities.
Featured Huntingtons Disease Studies
Highlighted recruiting studies for huntingtons disease, selected by enrollment size and research scope.
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database o...
HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease
HDClarity will seek at least 2500 research participants at different stages of Huntington's disease (HD). The primary objective is to collect a high quality CSF sample for evaluation of biomarkers and pathways that will enable the development of novel treatments for HD. The secondary objective is to generate a high quality plasma sample collection matching the CSF collections, which will also be u...
Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease
The purpose of this prospective observational study is to collect data from participants who have recently had an allogenic Stem Cell Transplant(alloSCT) and are at risk of Chronic Graft Versus Host Disease(cGVHD)
Frequently Asked Questions About Huntingtons Disease Clinical Trials
Are there huntingtons disease clinical trials near me?
Yes, there are 78 huntingtons disease clinical trials currently recruiting across 94+ cities in the United States, including Baltimore, Maryland; Birmingham, Alabama; Pittsburgh, Pennsylvania. Browse the studies above to find one at a location convenient for you.
How do I join a huntingtons disease clinical trial?
To join a huntingtons disease clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are huntingtons disease clinical trials free?
Yes, participation in huntingtons disease clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of huntingtons disease treatments are being studied?
Current huntingtons disease clinical trials are testing a range of approaches across NA (31 studies), PHASE4 (11 studies), PHASE2 (10 studies), PHASE1 (6 studies), PHASE3 (3 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 66 research organizations.
Is it safe to participate in huntingtons disease clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov