NCT06704061 · Palo Alto Veterans Institute for Research
Online Yoga vs Acceptance and Commitment Therapy for Treating Chronic Musculoskeletal Pain
What this study is about
This study will compare online yoga with Acceptance and Commitment Therapy (ACT), an established treatment for chronic pain. We will compare the effectiveness of the two treatments for reducing chronic musculoskeletal pain in veterans.
View original scientific description
This study will compare online yoga with Acceptance and Commitment Therapy (ACT), an established treatment for chronic pain. We will compare the efficacy of the two treatments for reducing chronic musculoskeletal pain in veterans.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Veteran of the United States Armed Forces ≥ 18 years old
- Chronic pain \> 6 months related to at least one musculoskeletal pain-related diagnosis indicated by an ICD-9 or -10 code
- Minimum pain intensity at screening ≥4 on a 0-10 using the Defense and Veterans Pain Rating Scale (DVPRS)
- Not begun new pain treatments or medications in the past month
- Stable medication regimen for at least 4 weeks prior to entry to the study
- English literacy
- Internet connection at home
Exclusion criteria
- Participation in another clinical trial, unless given prior authorization from both our research team and that of the other study
- Back surgery within the last 12 months
- Back pain potentially attributed to a specific known condition
- Baseline pain \<4 or ≥9 on a 0-10 Numeric Rating Scale
- Unstable, serious coexisting medical illness, mental illness or psychiatric conditions
- Attended or practiced yoga ≥ 1 x in the past 12 months
- Current suicidal intent or plan
- Has received ACT in the past
Where
- Palo Alto, California
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jan 29, 2026 · Source of record for eligibility and locations