Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Chronic Pain Clinical Trials
Chronic Pain clinical trials are recruiting across 118 cities. Here are the cities with the most active studies:
Chronic Pain Trial Phases
71 research organizations are sponsoring chronic pain trials.
About Chronic Pain
Chronic pain is pain that persists for more than three months, often beyond the expected healing period. It affects approximately 20% of adults worldwide and can significantly impact quality of life. Management involves a multimodal approach including medications, physical therapy, and interventional procedures.
Clinical trials are advancing new treatments for chronic pain. Currently, 100 studies are recruiting a combined 58,736 participants across the United States. Research is being conducted by 71 organizations including Boston Scientific Corporation, Eli Lilly and Company, Telethon Kids Institute and 68 others.
2026 Chronic Pain Research Landscape
As of July 2026, the chronic pain clinical trial landscape includes 100 actively recruiting studies across 118 cities in the United States. These studies are collectively seeking 58,736 participants, with an average enrollment target of 587 per study.
The research spans multiple phases of development: 58 studies are in NA, 12 studies are in PHASE2, 6 studies are in PHASE3, 3 studies are in PHASE4, 2 studies are in PHASE1. The presence of Phase 3 trials indicates that some chronic pain treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 71 different organizations, including Boston Scientific Corporation, Eli Lilly and Company, Telethon Kids Institute, Abbott Medical Devices, Stanford University, and 66 others. The large number of sponsors reflects significant research interest and investment in chronic pain treatment advancement.
Geographically, chronic pain trials are most concentrated in Phoenix, Arizona (8 trials); San Diego, California (6 trials); Ann Arbor, Michigan (6 trials); San Francisco, California (5 trials); Chicago, Illinois (5 trials) and 7 other cities.
Featured Chronic Pain Studies
Highlighted recruiting studies for chronic pain, selected by enrollment size and research scope.
Patient Retrospective Outcomes (PRO)
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-state addenda (DSA) and intervention-specific appendices (ISAs). The ISAs may start independently of other ISAs as interventions become available for clinical testing.
A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children
The purpose of this study is to investigate the prevalence, risk factors and consequences of chronic post-surgical pain in children aged 0-16 years through a number of questionnaires completed at various timepoints, from before surgery up to 1 year post surgery.
Frequently Asked Questions About Chronic Pain Clinical Trials
Are there chronic pain clinical trials near me?
Yes, there are 100 chronic pain clinical trials currently recruiting across 118+ cities in the United States, including Phoenix, Arizona; San Diego, California; Ann Arbor, Michigan. Browse the studies above to find one at a location convenient for you.
How do I join a chronic pain clinical trial?
To join a chronic pain clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are chronic pain clinical trials free?
Yes, participation in chronic pain clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of chronic pain treatments are being studied?
Current chronic pain clinical trials are testing a range of approaches across NA (58 studies), PHASE2 (12 studies), PHASE3 (6 studies), PHASE4 (3 studies), PHASE1 (2 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 71 research organizations.
Is it safe to participate in chronic pain clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov