Durham, NCNCT06747871Now EnrollingIRB Ready

Chronic Pain Clinical Trial in Durham, NC

Access cutting-edge chronic pain treatment through this clinical trial at a research site in Durham. Study-provided care at no cost to qualified participants.

Sponsored by Duke University

Quick Self-Assessment

See if you qualify for this Durham location

Preparing your pre-screening questions…

Expert Care in Durham

Access chronic pain specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related chronic pain treatment provided free

Apply for This Durham Location

Check if you qualify for this chronic pain clinical trial in Durham, NC

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Durham

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Durham site if eligible
  4. 4Begin participation

About This Chronic Pain Study in Durham

The purpose of this study is to evaluate the effects of switching to very low nicotine content (VLNC) cigarettes versus normal nicotine content (NNC) cigarettes on craving, withdrawal, and pain among individuals with chronic pain who smoke cigarettes daily and are attending office-based buprenorphine treatment (OBBT).

Sponsor: Duke University

Who Can Participate

Inclusion Criteria

Aged 21+ years who smoke cigarettes daily
Chronic non-cancer musculoskeletal pain secondary to structural changes (e.g., low back pain, osteoarthritis)
Have received stable office-based buprenorphine treatment for opioid use disorder for at least 30 days
Self-report smoking at least 10 cigarettes/day
Expired breath carbon monoxide (CO) level \>8 ppm
Have a smartphone capable of running software for ecological momentary assessment
Open to exploring the possibility of quitting smoking

Exclusion Criteria

Pain specifically due to cancer
Other significant health problems
Major surgery within the past 6 months or planned surgery within the timeframe of the study
Current disability litigation
Use of electronic cigarettes or other non-cigarette tobacco products \> 9 of the past 30 days
Current use of nicotine replacement therapy or other cessation treatment
Current daily or near-daily cannabis use
History of psychotic disorder
Acute suicidality or current unstable psychiatric disorder
Positive pregnancy test
Actively seeking smoking cessation treatment

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Durham?

Yes, this clinical trial (NCT06747871) has an active research site in Durham, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Chronic Pain Treatment Options in Durham, NC

If you're searching for chronic pain treatment options in Durham, NC, this clinical trial (NCT06747871) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Durham research site is actively enrolling participants for this clinical trial. You'll receive care from experienced chronic pain specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all chronic pain clinical trials near you to find additional studies recruiting in your area.

More Chronic Pain Trials in Durham, NC

See all chronic pain clinical trials recruiting in Durham — not just this study.

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Secure · Expert Care · Durham, NC