NCT06181994 · Montefiore Medical Center
Middle Meningeal Artery Embolization (MMAE) Outcomes for Chronic Subdural Hematoma (cSDH)
(MESH)
What this study is about
This multi-center reviewing past data group of participants study aims to investigate the real-world outcomes of chronic subdural hematoma treated with MMAE, including clinical effectiveness, recurrence rates, and safety profile.
View original scientific description
This multi-center retrospective cohort study aims to investigate the real-world outcomes of chronic subdural hematoma treated with MMAE, including clinical effectiveness, recurrence rates, and safety profile.
Primary outcome measures
Reaccumulation of Hematoma
Time frame: Within 1 month post MMAE
The percentage of patients who were determined to have a reaccumulation of their hematoma will be tabulated and reported
Rescue surgical evacuation
Time frame: Between 1-3 months post MMAE
The percentage of patients who were determined to require rescue surgical evacuation of their hematoma will be tabulated and reported
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Consecutive adult patients (18 yrs. of age or older)
- Endovascular embolization of middle meningeal artery using any embolization material: PVA particles; Onyx, nBCA glue; dimethyl sulfoxide, microcoils, PVA with microcoils
Exclusion criteria
- Endovascular embolization of middle meningeal artery using any other embolization material
Where
- Coral Gables, Florida
- Jacksonville, Florida
- Orlando, Florida
- Chicago, Illinois
- Iowa City, Iowa
- Boston, Massachusetts
- Burlington, Massachusetts
- Rochester, Minnesota
- The Bronx, New York
- Danville, Pennsylvania
- Philadelphia, Pennsylvania
- Houston, Texas
And 1 more location — see the full list below.
Collaborators
Geisinger Clinic, Heidelberg University, Henri Mondor University Hospital, Ospedale Policlinico San Martino, Ospedale San Raffaele, Lehigh Valley Hospital, Mayo Clinic, Medical University of South Carolina, New York University, Oregon Health and Science University, Sisters of Mercy University Hospital, Unity Health Toronto, Sutter Health, University of Iowa, Thomas Jefferson University, University Health Network, Toronto, University Hospital, Bordeaux, University of Alabama at Birmingham, University of South Florida, University of Washington, Cornell University, Westchester Medical Center
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jan 7, 2026 · Source of record for eligibility and locations