Cleveland, OHNCT06673095Now EnrollingIRB Ready

Clinical Stage IA Cutaneous Melanoma AJCC v8 Clinical Trial in Cleveland, OH

Access cutting-edge clinical stage ia cutaneous melanoma ajcc v8 treatment through this clinical trial at a research site in Cleveland. Study-provided care at no cost to qualified participants.

Sponsored by OHSU Knight Cancer Institute

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Expert Care in Cleveland

Access clinical stage ia cutaneous melanoma ajcc v8 specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related clinical stage ia cutaneous melanoma ajcc v8 treatment provided free

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Check if you qualify for this clinical stage ia cutaneous melanoma ajcc v8 clinical trial in Cleveland, OH

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Why Participate?

  • No-Cost Study Care

  • Local to Cleveland

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Cleveland site if eligible
  4. 4Begin participation

About This Clinical Stage IA Cutaneous Melanoma AJCC v8 Study in Cleveland

This clinical trial compares the effect of a narrow surgical excision (removal) to a wide excision for the treatment of adults with invasive cutaneous melanoma. Currently the standard of care is to take wide margins (boarder of healthy tissue surrounding the melanoma) when removing melanoma. Narrow margin excision removes a smaller amount of healthy tissue when surgically removing the melanoma. Narrow margin excision may be effective in removing the melanoma while also reducing surgical complications and improving quality of life for adults with invasive cutaneous melanoma.

Sponsor: OHSU Knight Cancer Institute

Who Can Participate

Inclusion Criteria

Participants or legally authorized representatives (LAR) must provide written informed consent before any study-specific procedures or interventions are performed
Age ≥ 18 years; all biological gender identities and racial/ethnic groups will be included
Participants must have histologically confirmed primary cutaneous melanoma. Acral melanomas are eligible.
Participants must have one of the following:
American Joint Committee on Cancer (AJCC) 8th Ed clinical stage IA disease with Breslow thickness \> 0.5 mm AND at least one high-risk feature (Mitotic rate ≥ 2/mm2, age ≤ 42, lymphovascular invasion, head/neck location)
AJCC 8th Ed Clinical Stage IB melanoma
If a melanoma is widely transected and the true Breslow depth is uncertain, then to be eligible for this trial, the melanoma must be re-biopsied to ascertain an accurate Breslow depth.
The index melanoma must be classified as low risk on the Merlin Assay (SkylineDx)
Study intervention (surgery) must be completed within 120 days of the original diagnostic biopsy
Eastern Cooperative Oncology Group (ECOG) performance status ≤ 2 (Karnofsky ≥ 50%)
Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial
Participants with a history of HIV infection are eligible
Participants can speak, read and write in English or Spanish

Exclusion Criteria

Uncertain diagnosis of melanoma (i.e. severely dysplastic nevi, melanocytic lesion of unknown malignant potential, atypical intraepidermal melanocytic proliferations)
The patient has already undergone wide local excision at the site of the primary index lesion
The patient has a pure desmoplastic melanoma. A pure desmoplastic melanoma is defined as being \> 90% desmoplastic type. Melanomas with \< 90% desmoplastic type may be included in this trial
Mucosal and ocular melanomas are also excluded, as these are approached differently for surgical excision
Physical, clinical, radiographic, or pathologic evidence of satellite, in-transit, regional, or distant metastatic melanoma
Participants with known or suspected cancer with regional or distant metastasis are excluded from this clinical trial because this trial is aimed at evaluating the control of localized disease
The patient has undergone surgery on a separate occasion to clear the lymph nodes of the probable draining lymphatic field, including a sentinel lymph node biopsy, of the index melanoma
Planned adjuvant radiotherapy to the primary melanoma site after excision
Participant is unwilling or unable to comply with study procedures

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cleveland?

Yes, this clinical trial (NCT06673095) has an active research site in Cleveland, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Clinical Stage IA Cutaneous Melanoma AJCC v8 Treatment Options in Cleveland, OH

If you're searching for clinical stage ia cutaneous melanoma ajcc v8 treatment options in Cleveland, OH, this clinical trial (NCT06673095) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cleveland research site is actively enrolling participants for this clinical trial. You'll receive care from experienced clinical stage ia cutaneous melanoma ajcc v8 specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all clinical stage ia cutaneous melanoma ajcc v8 clinical trials near you to find additional studies recruiting in your area.

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