Las Vegas, NVNCT07342478Now EnrollingIRB Ready

CLL / SLL Clinical Trial in Las Vegas, NV

Access cutting-edge cll / sll treatment through this phase 3 clinical trial at a research site in Las Vegas. Study-provided care at no cost to qualified participants.

Sponsored by Newave Pharmaceutical Inc

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Expert Care in Las Vegas

Access cll / sll specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related cll / sll treatment provided free

Apply for This Las Vegas Location

Check if you qualify for this cll / sll clinical trial in Las Vegas, NV

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Las Vegas

    Convenient for NV residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Las Vegas site if eligible
  4. 4Begin participation

About This CLL / SLL Study in Las Vegas

This is a Phase 3, randomized, open-label, multicenter study comparing rocbrutinib (LP-168) versus pirtobrutinib in adult participants with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have previously received a covalent Bruton's tyrosine kinase inhibitor (cBTKi). Approximately 306 participants will be randomized 1:1 to receive rocbrutinib 200 mg orally once daily or pirtobrutinib 200 mg orally once daily, administered continuously in 28-day cycles until disease progression, unacceptable toxicity, withdrawal of consent, or other discontinuation criteria are met. Randomization will be stratified by presence of del(17p)/TP53 mutation (yes/no), reason for discontinuation of prior cBTKi therapy (toxicity vs disease progression), prior exposure to a BCL2 inhibitor (yes/no), and region (United States/China/rest of world). The primary endpoint is progression-free survival (PFS) assessed by an independent review committee (IRC) using iwCLL 2018 criteria for CLL and Lugano 2014 criteria for SLL. Key secondary objectives include overall survival, overall response rate, time-to-event outcomes, and safety/tolerability; exploratory objectives include health-related quality of life and biomarker assessments.

Sponsor: Newave Pharmaceutical Inc

Who Can Participate

Inclusion Criteria

Age ≥18 years;
Histologically confirmed CLL/SLL iwCLL 2018;
Relapsed or refractory disease requiring treatment;
Previously treated with prior lines of therapy including a covalent BTK inhibitor;
Measurable disease;
Adequate marrow, hepatic, and renal function;
TP53 mutation status confirmed by NGS;
17p deletion status confirmed by FISH;

Exclusion Criteria

Prior ncBTKi or BTK degraders;
Richter's transformation;
Confirmed prolymphocytic leukemia;
Uncontrolled comorbidities or infections;
Known CNS involvement by CLL/SLL;
Prior malignancy requiring active treatment (except certain adequately treated cancers) per protocol;
Pregnancy or breastfeeding;
Concomitant medications or conditions prohibited by protocol (e.g., strong drug-drug interaction risk);

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Las Vegas?

Yes, this clinical trial (NCT07342478) has an active research site in Las Vegas, NV that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

CLL / SLL Treatment Options in Las Vegas, NV

If you're searching for cll / sll treatment options in Las Vegas, NV, this clinical trial (NCT07342478) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Las Vegas research site is actively enrolling participants for this phase 3 clinical trial. You'll receive care from experienced cll / sll specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all cll / sll clinical trials near you to find additional studies recruiting in your area.

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