Nashville, TNNCT07544589Now EnrollingIRB Ready

Colorectal Cancer Clinical Trial in Nashville, TN

Access cutting-edge colorectal cancer treatment through this clinical trial at a research site in Nashville. Study-provided care at no cost to qualified participants.

Sponsored by Dispatch Biotherapeutics

Quick Self-Assessment

See if you qualify for this Nashville location

Preparing your pre-screening questions…

Expert Care in Nashville

Access colorectal cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related colorectal cancer treatment provided free

Apply for This Nashville Location

Check if you qualify for this colorectal cancer clinical trial in Nashville, TN

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Nashville

    Convenient for TN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Nashville site if eligible
  4. 4Begin participation

About This Colorectal Cancer Study in Nashville

This is a Phase 1, multicenter, open-label study of DISP-10, a combination therapy consisting of DV-10 (adenovirus) and idecabtagene vicleucel (ide-cel, BCMA-directed chimeric antigen receptor \[CAR\] T), in adult participants with advanced gastrointestinal (GI) cancers. The study will consist of 2 parts: dose-escalation (Part 1) and dose-expansion (Part 2). Part 1 of the study will evaluate the safety and tolerability of increasing dose levels of DISP-10 to establish the recommended dose for expansion (RDE); Part 2 will evaluate the safety and efficacy of DISP-10 in participants treated at the RDE.

Sponsor: Dispatch Biotherapeutics

Who Can Participate

Inclusion Criteria

Histologically confirmed advanced or metastatic esophageal, gastroesophageal junction, gastric adenocarcinoma, or colorectal adenocarcinoma
Measurable disease according to RECIST v1.1 and at least 1 additional site of disease amenable to biopsy
Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
Aged ≥18 years at time of signing informed consent
Adequate organ function Key

Exclusion Criteria

Previous solid organ or hematopoietic cell transplant
Evidence of rapid disease progression, defined as radiographic or clinical progression within 3 months of the most recent prior line of therapy
Known history of hepatitis B or HIV infection
Previous or concurrent malignancy except if curatively treated more than 3 years prior to enrollment
Known active central nervous system (CNS) metastases
Clinically significant pleural or pericardial effusion or peritoneal carcinomatosis
Active treatment with antiviral agents
History of severe hypersensitivity to fludarabine or cyclophosphamide
Prior therapies/treatments with oncolytic viruses or T cell derived cellular therapy

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Nashville?

Yes, this clinical trial (NCT07544589) has an active research site in Nashville, TN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Colorectal Cancer Treatment Options in Nashville, TN

If you're searching for colorectal cancer treatment options in Nashville, TN, this clinical trial (NCT07544589) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Nashville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced colorectal cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all colorectal cancer clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Nashville, TN