Lebanon, NHNCT05780684Now EnrollingIRB Ready

Colorectal Cancer Clinical Trial in Lebanon, NH

Access cutting-edge colorectal cancer treatment through this clinical trial at a research site in Lebanon. Study-provided care at no cost to qualified participants.

Sponsored by Dartmouth-Hitchcock Medical Center

Quick Self-Assessment

See if you qualify for this Lebanon location

Preparing your pre-screening questions…

Expert Care in Lebanon

Access colorectal cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related colorectal cancer treatment provided free

Apply for This Lebanon Location

Check if you qualify for this colorectal cancer clinical trial in Lebanon, NH

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Lebanon

    Convenient for NH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Lebanon site if eligible
  4. 4Begin participation

About This Colorectal Cancer Study in Lebanon

This is a single-arm clinical trial to evaluate the feasibility of a chemotherapy regimen using adaptive, individualized dose escalation of 5-FU chemotherapy for patients who have good tolerance of the initial dose. Study participants will also receive oxaliplatin chemotherapy together with 5-FU, at standard doses. The goal of the study is to examine the feasibility and effectiveness of this approach, using individualized dose escalation of 5-FU in patients who do not have serious side effects at lower doses.

Sponsor: Dartmouth-Hitchcock Medical Center

Who Can Participate

Inclusion Criteria

Age ≥ 18 years
Diagnosis of metastatic or locally advanced/inoperable colorectal cancer or non-colorectal gastrointestinal cancer (including cancers of the stomach, esophagus, appendix, small bowel, and ampulla)
Clinically appropriate staging imaging of the chest, abdomen, and pelvis performed within 30 days prior to registration
ECOG Performance Status: 0-1

Exclusion Criteria

Any prior receipt of oxaliplatin or fluoropyrimidine chemotherapy (other than radiation-sensitizing fluoropyrimidine chemotherapy)
Prior receipt of systemic chemotherapy in the 6 months prior to Day 1 of Cycle 1 of FOX (other than radiation-sensitizing chemotherapy)
Known mismatch repair deficiency or microsatellite instability-high disease
Known dihydropyrimidine dehydrogenase (DPD) deficiency, as identified by clinically indicated screening
Any confirmed second malignancy that is likely to require systemic therapy during the course of the six-month study period, in the opinion of the enrolling investigator
Any of the following baseline laboratory abnormalities:
Absolute neutrophil count (ANC) \< 2,500/mm3
Platelet count \< 100,000/mm3
Hemoglobin \< 9 g/dL
Creatinine \> 1.5 x ULN
Total bilirubin \> 1.5 x ULN
AST/ALT \> 5 x ULN
Patients who are unable to provide informed consent
Patients who are pregnant or breastfeeding
Patients who are incarcerated, homeless, or have active substance use disorders

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Lebanon?

Yes, this clinical trial (NCT05780684) has an active research site in Lebanon, NH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Colorectal Cancer Treatment Options in Lebanon, NH

If you're searching for colorectal cancer treatment options in Lebanon, NH, this clinical trial (NCT05780684) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Lebanon research site is actively enrolling participants for this clinical trial. You'll receive care from experienced colorectal cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all colorectal cancer clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Lebanon, NH