Is this constipation clinical trial recruiting?

Yes, this constipation study is currently recruiting and enrolling participants at 1 locations.

Where can I join this constipation trial?

This trial has 1 active site including Memphis, Tennessee.

Who is eligible for this constipation study?

This constipation trial is targeting 30 participants. Detailed eligibility criteria including age requirements and medical history are listed on this page.

What phase is this constipation trial?

This is a NA clinical trial for constipation, sponsored by University of Memphis. It is currently recruiting participants.

Who can participate in this Constipation study?

Eligibility varies by study, but generally includes adults diagnosed with Constipation who meet specific medical criteria. Complete the interest form above to learn if you may qualify.

Is the study available in Memphis, Tennessee?

Yes! This study has active research sites in Memphis. When you express interest, you'll be connected with the site nearest to you.

What are the benefits of joining a clinical trial for Constipation?

Participants often receive: access to new treatments before they're widely available, close monitoring by medical professionals, study-related care at no cost, and the opportunity to contribute to medical research.

NCT07215351 · University of Memphis

Impact of the Inno Cleanse Dietary Supplement on Gut Health and Associated Variables in Healthy Men and Women

What this study is about

View original scientific description

The purpose of the present study is to investigate the impact of a natural dietary supplement, Inno Cleanse™, to reduce bloating in a population of otherwise healthy men and women, who claim to feel frequently bloated. Inno CleanseTM dietary supplement is manufactured in the United States under current Good Manufacturing Practices (cGMP) and is marketed by InnoSupps as a digestive health aid. It is sold in the United States on the company's website, Amazon, and in many large retail outlets. It remains a very popular product, with close to 1.4 million units sold since 2020, with a reported 66,000 units sold in the past three months. Despite the prevalence of dietary supplements identifying as digestive aids, detoxification, and cleanses, very little research has been done to determine their effectiveness. The product appears to be well-designed, with multiple ingredients included which have scientific evidence of effectiveness. That said, and despite the overall positive reviews, there is no known clinical research to support the product's effectiveness. Therefore, the aim of this study is to evaluate the efficacy of the Inno Cleanse product to reduce bloating and result in other positive outcomes (weight loss). This study will be run as a double-blind placebo-controlled trial, in which subjects will use the product or placebo for two weeks. It is hypothesized that treatment with the dietary supplement Inno Cleanse will result in reduced bloating, as evidenced by self-reported reductions in bloating and hunger, as well as moderate weight loss and a reduction in body circumference measures due to the reduced bloating. In addition, multiple anecdotal reports of improved skin health have been noted in those using the product. Additionally, routine blood and urine sample analysis will be performed as a secondary outcome, as a safety measure.

Interventions

DIETARY_SUPPLEMENT

Dietary supplement for digestive health

Dietary supplement contains cascara sagrada bark powder, cape aloe leaves extract, senna leaf powder, frangula bark powder fennel seed powder, bentonite clay, burdock root powder, licorice root extract, slippery elm bark powder, Capiscum annuum L. Fruit powder, milk thistle seed powder, hydroxypropyl methylcellulose, and silicon dioxide.

DIETARY_SUPPLEMENT

placebo capsule

Contains hydroxypropyl methylcellulose and cellulose

Primary outcome measures

Alanine transaminase

Time frame: baseline

Alanine transaminase measured as part of metabolic panel in international units per liter

Alanine transaminase