Houston, TXNCT04494724Now EnrollingIRB Ready

COVID-19 Infection Clinical Trial in Houston, TX

Access cutting-edge covid-19 infection treatment through this phase 2 clinical trial at a research site in Houston. Study-provided care at no cost to qualified participants.

Sponsored by The Methodist Hospital Research Institute

Quick Self-Assessment

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Expert Care in Houston

Access covid-19 infection specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related covid-19 infection treatment provided free

Apply for This Houston Location

Check if you qualify for this covid-19 infection clinical trial in Houston, TX

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Houston

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Houston site if eligible
  4. 4Begin participation

About This COVID-19 Infection Study in Houston

The purpose of this study is to investigate the effectiveness and safety of treatment with clazakizumab compared to a placebo (inactive substance). We are proposing to try this drug to treat coronavirus disease 2019 (COVID-19) infection. Patients with COVID-19 infection have been shown to have increases in certain inflammatory processes. Clazakizumab is an antibody (immune system protein) that blocks certain inflammatory processes. The treatment plan is to attempt to inhibit or block these inflammatory processes in order to try to limit the damage COVID-19 causes to the lungs.

Sponsor: The Methodist Hospital Research Institute

Who Can Participate

Inclusion Criteria

Age \>18 at the time of screening.
Participant or legally authorized representative (LAR) must be able to understand and provide informed consent.
Hospitalized with coronavirus disease (COVID-19) confirmed by polymerase chain reaction (PCR) assay from any specimen (eg, respiratory, blood, urine, stool, other bodily fluid) within the prior 72 hours.
C-reactive protein (CRP) \> 3.5 mg/dL
Evidence of pulmonary involvement with at least 2 of the following:
oxygen saturation at rest in ambient air with peripheral capillary oxygen saturation (SpO2) ≤ 94%
tachypnea with resting respiration rate \> 25 breaths/minute
Partial pressure of oxygen (PaO2)/initial fraction of inspired oxygen (FiO2) ≤ 300 mmHg
Chest imaging (radiograph, CT, or ultrasound) with abnormalities consistent COVID-19 pneumonia

Exclusion Criteria

Previous hypersensitivity or allergic reactions to clazakizumab
Lactating or pregnant females
Patients with latent tuberculosis (TB) and who are not receiving treatment
Patients with active TB
Patients with known active inflammatory bowel disease, untreated diverticulitis, or gastrointestinal perforation
Requiring mechanical ventilation or extracorporeal membrane oxygenation (ECMO)
A significantly abnormal general serum screening lab result defined as a white blood cell (WBC) count \< 3.0 X 10\^3/mL, a hemoglobin (Hgb) \< 8.0 g/dL, a platelet count \< 50 X 10\^3/mL, an aspartate aminotransferase (AST) or alanine aminotransferase (ALT) \> 5 times upper limit normal
Participation in another clinical trial investigating COVID-19-aimed agents
Presence of any medical or psychosocial condition, which the investigator believes, would hinder adherence to the study requirements.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Houston?

Yes, this clinical trial (NCT04494724) has an active research site in Houston, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

COVID-19 Infection Treatment Options in Houston, TX

If you're searching for covid-19 infection treatment options in Houston, TX, this clinical trial (NCT04494724) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Houston research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced covid-19 infection specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all covid-19 infection clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Houston, TX