Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for COVID-19 Clinical Trials
COVID-19 clinical trials are recruiting across 111 cities. Here are the cities with the most active studies:
COVID-19 Trial Phases
68 research organizations are sponsoring covid-19 trials.
About COVID-19
COVID-19 is an infectious disease caused by the SARS-CoV-2 virus that primarily affects the respiratory system. Long COVID (PASC) involves persistent symptoms weeks or months after initial infection. Treatment includes antiviral medications, monoclonal antibodies, and supportive care.
Clinical trials are advancing new treatments for covid-19. Currently, 100 studies are recruiting a combined 664,759 participants across the United States. Research is being conducted by 68 organizations including VA Office of Research and Development, Scripps Translational Science Institute, Yale University and 65 others.
2026 COVID-19 Research Landscape
As of July 2026, the covid-19 clinical trial landscape includes 100 actively recruiting studies across 111 cities in the United States. These studies are collectively seeking 664,759 participants, with an average enrollment target of 6,648 per study.
The research spans multiple phases of development: 27 studies are in NA, 16 studies are in PHASE2, 9 studies are in PHASE3, 9 studies are in PHASE1, 3 studies are in PHASE4, 1 study is in EARLY_PHASE1. The presence of Phase 3 trials indicates that some covid-19 treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 68 different organizations, including VA Office of Research and Development, Scripps Translational Science Institute, Yale University, Masaryk University, M.D. Anderson Cancer Center, and 63 others. The large number of sponsors reflects significant research interest and investment in covid-19 treatment advancement.
Geographically, covid-19 trials are most concentrated in New York, New York (12 trials); Boston, Massachusetts (9 trials); Chicago, Illinois (9 trials); Baltimore, Maryland (9 trials); Houston, Texas (8 trials) and 7 other cities.
Featured COVID-19 Studies
Highlighted recruiting studies for covid-19, selected by enrollment size and research scope.
Clinical Outcomes and Pharmacotherapy Effectiveness in the VA Health Care System (COPE-VA)
The purpose of this study is to comprehensively describe the temporal and geographic utilization of COVID-19 therapies used for mild to moderate disease during different periods of SARS-CoV-2 variant circulation as well as to compare demographic and clinical characteristics of Veterans who are treated or do not receive these different therapies. The investigators will also perform similar descript...
The Long COVID-19 Wearable Device Study
To further characterize Long COVID-19 by collecting data from individuals who already own wearable devices or are provided with a wearable device along with basic and enhanced educational materials to determine if both can improve Long COVID-19 symptom management and post-exertional malaise.
Addressing Vaccine Acceptance in Carceral Settings Through Community Engagement
The goal of this study is to reduce morbidity and mortality from COVID-19 amongst people who are detained in and work in correctional facilities. The overall objective is to identify feasible and effective interventions to improve vaccine uptake in correctional facilities and study the effectiveness of these interventions through rapid cycle, cluster randomized trials in the Pennsylvania prison sy...
Frequently Asked Questions About COVID-19 Clinical Trials
Are there covid-19 clinical trials near me?
Yes, there are 100 covid-19 clinical trials currently recruiting across 111+ cities in the United States, including New York, New York; Boston, Massachusetts; Chicago, Illinois. Browse the studies above to find one at a location convenient for you.
How do I join a covid-19 clinical trial?
To join a covid-19 clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are covid-19 clinical trials free?
Yes, participation in covid-19 clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of covid-19 treatments are being studied?
Current covid-19 clinical trials are testing a range of approaches across NA (27 studies), PHASE2 (16 studies), PHASE3 (9 studies), PHASE1 (9 studies), PHASE4 (3 studies), EARLY_PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 68 research organizations.
Is it safe to participate in covid-19 clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov