Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Influenza Clinical Trials
Influenza clinical trials are recruiting across 106 cities. Here are the cities with the most active studies:
Influenza Trial Phases
41 research organizations are sponsoring influenza trials.
About Influenza
Influenza is a contagious respiratory illness caused by influenza viruses that infect the nose, throat, and lungs. It causes millions of illnesses and thousands of deaths annually. Prevention through vaccination is the primary strategy, with antiviral medications available for treatment.
Clinical trials are advancing new treatments for influenza. Currently, 59 studies are recruiting a combined 1,722,547 participants across the United States. Research is being conducted by 41 organizations including Kaiser Permanente, St. Jude Children's Research Hospital, GlaxoSmithKline and 38 others.
2026 Influenza Research Landscape
As of October 2026, the influenza clinical trial landscape includes 59 actively recruiting studies across 106 cities in the United States. These studies are collectively seeking 1,722,547 participants, with an average enrollment target of 29,196 per study.
The research spans multiple phases of development: 15 studies are in NA, 11 studies are in PHASE2, 10 studies are in PHASE1, 5 studies are in PHASE3, 4 studies are in PHASE4, 2 studies are in EARLY_PHASE1. The presence of Phase 3 trials indicates that some influenza treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 41 different organizations, including Kaiser Permanente, St. Jude Children's Research Hospital, GlaxoSmithKline, University of Colorado, Denver, National Institute of Allergy and Infectious Diseases (NIAID), and 36 others. The large number of sponsors reflects significant research interest and investment in influenza treatment advancement.
Geographically, influenza trials are most concentrated in Atlanta, Georgia (8 trials); Chicago, Illinois (6 trials); San Diego, California (5 trials); Bethesda, Maryland (5 trials); Boston, Massachusetts (4 trials) and 7 other cities.
Featured Influenza Studies
Highlighted recruiting studies for influenza, selected by enrollment size and research scope.
Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years
This study will evaluate the relative vaccine effectiveness of quadrivalent adjuvanted inactivated influenza vaccine (aIIV4) versus quadrivalent high-dose inactivated influenza vaccine (HD-IIV4) in preventing polymerase chain reaction (PCR)-confirmed influenza and influenza-related outcomes in adults ≥65 years of age during the 2023/24, 2024/25, and 2026/27 influenza seasons. The study is an obser...
Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility
The aims of this protocol are: to collect and store diseased and normal tissue and body fluid samples from new and returning patients at St. Jude Children's Research Hospital (SJCRH), affiliated sites and collaborating institutions; to collect and store samples from relatives of SJCRH patients; to collect and store retrospective and prospective pertinent corresponding clinical and laboratory data ...
A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age
This study will compare an investigational mRNA flu vaccine with a licensed flu vaccine in adults 65 years of age and older. Participants will receive one injection and will be followed during the flu season. The study will measure prevention of laboratory-confirmed flu illness, side effects, and immune responses.
Frequently Asked Questions About Influenza Clinical Trials
Are there influenza clinical trials near me?
Yes, there are 59 influenza clinical trials currently recruiting across 106+ cities in the United States, including Atlanta, Georgia; Chicago, Illinois; San Diego, California. Browse the studies above to find one at a location convenient for you.
How do I join a influenza clinical trial?
To join a influenza clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are influenza clinical trials free?
Yes, participation in influenza clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of influenza treatments are being studied?
Current influenza clinical trials are testing a range of approaches across NA (15 studies), PHASE2 (11 studies), PHASE1 (10 studies), PHASE3 (5 studies), PHASE4 (4 studies), EARLY_PHASE1 (2 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 41 research organizations.
Is it safe to participate in influenza clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated October 15, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated October 15, 2026 · Data from ClinicalTrials.gov