Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Tuberculosis Clinical Trials
Tuberculosis clinical trials are recruiting across 36 cities. Here are the cities with the most active studies:
Tuberculosis Trial Phases
32 research organizations are sponsoring tuberculosis trials.
About Tuberculosis
Tuberculosis (TB) is a bacterial infection that primarily affects the lungs and is caused by Mycobacterium tuberculosis. It remains one of the deadliest infectious diseases worldwide. Treatment involves a multi-drug antibiotic regimen taken for several months.
Clinical trials are advancing new treatments for tuberculosis. Currently, 37 studies are recruiting a combined 9,373 participants across the United States. Research is being conducted by 32 organizations including Centers for Disease Control and Prevention, National Institute of Allergy and Infectious Diseases (NIAID), University of Louisville and 29 others.
2026 Tuberculosis Research Landscape
As of July 2026, the tuberculosis clinical trial landscape includes 37 actively recruiting studies across 36 cities in the United States. These studies are collectively seeking 9,373 participants, with an average enrollment target of 253 per study.
The research spans multiple phases of development: 16 studies are in NA, 6 studies are in PHASE2, 2 studies are in PHASE3, 1 study is in PHASE4, 1 study is in PHASE1, 1 study is in EARLY_PHASE1. The presence of Phase 3 trials indicates that some tuberculosis treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 32 different organizations, including Centers for Disease Control and Prevention, National Institute of Allergy and Infectious Diseases (NIAID), University of Louisville, Wake Forest University Health Sciences, University of Alberta, and 27 others. The large number of sponsors reflects significant research interest and investment in tuberculosis treatment advancement.
Geographically, tuberculosis trials are most concentrated in Bethesda, Maryland (4 trials); Minneapolis, Minnesota (4 trials); Seattle, Washington (3 trials); Columbus, Ohio (3 trials); Denver, Colorado (2 trials) and 7 other cities.
Featured Tuberculosis Studies
Highlighted recruiting studies for tuberculosis, selected by enrollment size and research scope.
Assessment of the Safety, Tolerability, and Effectiveness of Rifapentine Given Daily for LTBI
This study is conducted to compare the safety and effectiveness of a novel short 6-week regimen of daily rifapentine (6wP, experimental arm) with a comparator arm of 12-16 weeks of rifamycin-based treatment (standard of care, control arm) of latent M. tuberculosis infection (LTBI). This trial is conducted among persons who are at increased risk of progression to tuberculosis (TB) and require trea...
Study of Mycobacterial Infections
This study will examine the symptoms, course of disease and treatment of non-tuberculous mycobacterial (NTM) infections, as well as the genetics involved in these infections. Patients with NTM have recurrent lung infections and sometimes infections of the skin and other organs as well. They may also have curvature of the spine, barrel chest, and heart valve weakness. The study will compare the fea...
Saline Versus Balanced Crystalloid in Traumatic Brain Injury
The goal of this clinical trial is to determine which crystalloid (saline or balanced) should be used in the critical management of Traumatic Brain Injury (TBI) in moderate or severe TBI patients. This trial will determine whether the use of saline or balanced crystalloids is associated with improved outcomes in TBI patients. Participants will 1. be given fluids through the veins, either saline ...
Frequently Asked Questions About Tuberculosis Clinical Trials
Are there tuberculosis clinical trials near me?
Yes, there are 37 tuberculosis clinical trials currently recruiting across 36+ cities in the United States, including Bethesda, Maryland; Minneapolis, Minnesota; Seattle, Washington. Browse the studies above to find one at a location convenient for you.
How do I join a tuberculosis clinical trial?
To join a tuberculosis clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are tuberculosis clinical trials free?
Yes, participation in tuberculosis clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of tuberculosis treatments are being studied?
Current tuberculosis clinical trials are testing a range of approaches across NA (16 studies), PHASE2 (6 studies), PHASE3 (2 studies), PHASE4 (1 study), PHASE1 (1 study), EARLY_PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 32 research organizations.
Is it safe to participate in tuberculosis clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 20, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 20, 2026 · Data from ClinicalTrials.gov