Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Hepatitis B Clinical Trials
Hepatitis B clinical trials are recruiting across 24 cities. Here are the cities with the most active studies:
Hepatitis B Trial Phases
9 research organizations are sponsoring hepatitis b trials.
About Hepatitis B
Hepatitis B is a liver infection caused by the hepatitis B virus that can become chronic and lead to cirrhosis, liver failure, or liver cancer. A vaccine can prevent infection. Treatment for chronic hepatitis B includes antiviral medications that suppress the virus.
Clinical trials are advancing new treatments for hepatitis b. Currently, 11 studies are recruiting a combined 731 participants across the United States. Research is being conducted by 9 organizations including Aligos Therapeutics, Mercy Medical Center, NYU Langone Health and 6 others.
2026 Hepatitis B Research Landscape
As of July 2026, the hepatitis b clinical trial landscape includes 11 actively recruiting studies across 24 cities in the United States. These studies are collectively seeking 731 participants, with an average enrollment target of 66 per study.
The research spans multiple phases of development: 6 studies are in PHASE1, 4 studies are in PHASE2, 1 study is in PHASE4. Early-phase studies suggest new therapeutic approaches are being explored for hepatitis b.
Research is being led by 9 different organizations, including Aligos Therapeutics, Mercy Medical Center, NYU Langone Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), GigaGen, Inc., and 4 others.
Geographically, hepatitis b trials are most concentrated in Baltimore, Maryland (4 trials); New York, New York (3 trials); Chandler, Arizona (2 trials); Coronado, California (1 trial); Garden Grove, California (1 trial) and 7 other cities.
Featured Hepatitis B Studies
Highlighted recruiting studies for hepatitis b, selected by enrollment size and research scope.
A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)
This is a Phase 2 study to evaluate efficacy and safety of 48 weeks of oral once daily monotherapy with ALG-000184 versus tenofovir disproxil fumarate (TDF) for chronic HBV infection.
Comparison Between 2-dose Versus 3-dose Regimens of Heplisav B in Cirrhosis
Investigators want to compare the seroconversion rates between two-dose and three-dose regimens of the hepatitis B vaccine (Heplisav B) among patients with cirrhosis, a randomized prospective study.
Adaptability of an Undetectable = Untransmissible Model for HBV
Persons with chronic hepatitis B (HBV) infection and active viremia are infectious and may transmit virus to others through blood/body fluid exposure. Immune tolerant treatment naive persons with hepatitis B infection express anxiety regarding disclosure of their infection status and significant fear of transmission to their partners leading to social isolation and impact on their personal lives. ...
Frequently Asked Questions About Hepatitis B Clinical Trials
Are there hepatitis b clinical trials near me?
Yes, there are 11 hepatitis b clinical trials currently recruiting across 24+ cities in the United States, including Baltimore, Maryland; New York, New York; Chandler, Arizona. Browse the studies above to find one at a location convenient for you.
How do I join a hepatitis b clinical trial?
To join a hepatitis b clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are hepatitis b clinical trials free?
Yes, participation in hepatitis b clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of hepatitis b treatments are being studied?
Current hepatitis b clinical trials are testing a range of approaches across PHASE1 (6 studies), PHASE2 (4 studies), PHASE4 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 9 research organizations.
Is it safe to participate in hepatitis b clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 18, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 18, 2026 · Data from ClinicalTrials.gov