Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Herpes Clinical Trials
Herpes clinical trials are recruiting across 5 cities. Here are the cities with the most active studies:
Herpes Trial Phases
4 research organizations are sponsoring herpes trials.
About Herpes
Herpes simplex virus (HSV) causes recurrent infections with painful blisters, most commonly oral (HSV-1) or genital (HSV-2). It is extremely common, affecting billions worldwide. Treatment includes antiviral medications to manage outbreaks and reduce transmission.
Clinical trials are advancing new treatments for herpes. Currently, 5 studies are recruiting a combined 1,899 participants across the United States. Research is being conducted by 4 organizations including National Institute of Allergy and Infectious Diseases (NIAID), Center for Clinical Studies, Texas, NYU Langone Health and 1 others.
2026 Herpes Research Landscape
As of July 2026, the herpes clinical trial landscape includes 5 actively recruiting studies across 5 cities in the United States. These studies are collectively seeking 1,899 participants, with an average enrollment target of 380 per study.
The research spans multiple phases of development: 2 studies are in PHASE2, 1 study is in PHASE1, 1 study is in PHASE4. Early-phase studies suggest new therapeutic approaches are being explored for herpes.
Research is being led by 4 different organizations, including National Institute of Allergy and Infectious Diseases (NIAID), Center for Clinical Studies, Texas, NYU Langone Health, National Cancer Institute (NCI).
Geographically, herpes trials are most concentrated in Bethesda, Maryland (3 trials); Houston, Texas (1 trial); Webster, Texas (1 trial); New York, New York (1 trial); Oklahoma City, Oklahoma (1 trial).
Featured Herpes Studies
Highlighted recruiting studies for herpes, selected by enrollment size and research scope.
Viral Infections in Healthy and Immunocompromised Hosts
Background: \- Viral infections are an important cause of illness and death in hospitalized patients as well as outpatients. New strains of viruses may appear and infect both healthy people and those with weak immune systems. A better understanding of these new virus strains (such as SARS-CoV-2, the virus that causes COVID-19) may help to control and prevent these infections. In particular, some ...
A Study That Collects Participant Data and Biospecimens to Analyze Pathogenic Exosomes That Mediate Increased Vascular Dementia Risk in Individuals With Herpes Zoster.
The purpose of this observational research study is to study if patients with herpes zoster, also known as Shingles, have a higher risk of vascular dysfunction (problems with blood vessels, including stroke) and vascular dementia (problems with mental decline as a result of decreased blood flow to the brain) compared to patients without herpes zoster. Patients are evaluated based on the group the...
Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population
Background: Shingles is a painful, blistering rash caused by the same virus that causes chickenpox. Shingrix is a vaccine approved to prevent shingles in healthy adults over age 50 and in immunocompromised adults over age 18. Researchers want to learn more about how people with HIV respond to Shingrix. Objective: To learn how Shingrix affects the immune response in people with HIV. Eligibility...
Frequently Asked Questions About Herpes Clinical Trials
Are there herpes clinical trials near me?
Yes, there are 5 herpes clinical trials currently recruiting across 5+ cities in the United States, including Bethesda, Maryland; Houston, Texas; Webster, Texas. Browse the studies above to find one at a location convenient for you.
How do I join a herpes clinical trial?
To join a herpes clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are herpes clinical trials free?
Yes, participation in herpes clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of herpes treatments are being studied?
Current herpes clinical trials are testing a range of approaches across PHASE2 (2 studies), PHASE1 (1 study), PHASE4 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 4 research organizations.
Is it safe to participate in herpes clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 15, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 15, 2026 · Data from ClinicalTrials.gov