Boston, MANCT07220733Now EnrollingIRB Ready

Critical Illness Clinical Trial in Boston, MA

Access cutting-edge critical illness treatment through this phase 1/2 clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Wandercraft

Quick Self-Assessment

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Expert Care in Boston

Access critical illness specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related critical illness treatment provided free

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Check if you qualify for this critical illness clinical trial in Boston, MA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Critical Illness Study in Boston

Patients admitted to the Intensive Care Unit (ICU) after thoracic surgery often experience complications related to immobility, such as muscle weakness, pulmonary issues, and longer recovery times. Early mobilization has been shown to improve outcomes, but its implementation is often limited by patient fragility and staff resources. This study will test the safety and feasibility of using the Atalante X, a self-balancing exoskeleton, in the Thoracic Surgical ICU at Brigham and Women's Hospital. The exoskeleton is designed to support patients in standing and walking, even if they have limited strength or balance, thereby reducing the physical burden on healthcare staff and increasing patient mobility. Eligible participants are adults recovering from thoracic surgery, who are debilitated (Johns Hopkins Highest Level of Mobility scale ≤ 5). Each participant will undergo up to 2-3 exoskeleton sessions per week for a maximum of 2 weeks. Sessions will be personalized, with progressive standing time and walking depending on patient tolerance. The primary goal is to evaluate the safety of exoskeleton use, measured by adverse events such as skin lesions, cardiovascular instability, or accidental device-related issues. The secondary goals are to evaluate: Feasibility (ability to deliver sessions as planned, duration of standing/walking, level of assistance needed), Usability (patient and staff satisfaction, ease of donning/doffing, staff workload), and Preliminary effectiveness (improvement in mobility scores at discharge). Results will provide early insights into whether robotic exoskeletons can be safely integrated into ICU rehabilitation programs after thoracic surgery.

Sponsor: Wandercraft

Who Can Participate

Inclusion Criteria

Above age of 18 years old,
Having undergone thoracic surgery that necessitated admission in the TSICU.
Debilitated as defined as a JH-HLM score of 5 or less

Exclusion Criteria

Height \< 6'3 feet or weight \> 220 lbs restrictions
Severe muscular spasticity of the lower extremities (Modified Ashworth Scale Grade 3 higher).
Current fractures or incomplete bone junctions in the spine, pelvis, and/or lower extremities
Osteoporosis or lower bone mineral density -3.5, and history(ies) of osteoporotic fracture(s).
Skin disorders including Stage I pressure injuries at the hip, lower limbs, and Exoskeleton contact areas, according to the National and European Pressure Ulcer Classification System (NPUAP-EPUAP).
Severe arthritis, acute arthritis, or synovitis after total or partial lower limb joint replacement.
Myocardial infarction or angina or ischemic heart disease within the last 6 months.
Uncorrectable leg length discrepancy over 2 cm when using additional correction tools.
III-IV spine scoliotic deformity.
Amputations and lower limb prostheses.
Adults who lack the capacity to provide informed consent
Cardiovascular instability as indicated by:
Presence of unstable ventricular or atrial arrhythmias
HR \< 40 or HR \> 140
Lactate \> 4.0 mmol/L
On moderate-high dose vasopressors/inotropes
Currently on VA ECMO
Respiratory instability as indicated by:
FiO2 \> 0.6
PEEP \> 12 cm H2O
RR \> 35 bpm
Currently on VV-ECMO
Unable to follow commands
Has bed rest orders

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT07220733) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Critical Illness Treatment Options in Boston, MA

If you're searching for critical illness treatment options in Boston, MA, this clinical trial (NCT07220733) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this phase 1/2 clinical trial. You'll receive care from experienced critical illness specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all critical illness clinical trials near you to find additional studies recruiting in your area.

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