Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Lupus Nephritis Clinical Trials
Lupus Nephritis clinical trials are recruiting across 101 cities. Here are the cities with the most active studies:
Lupus Nephritis Trial Phases
59 research organizations are sponsoring lupus nephritis trials.
About Lupus Nephritis
Lupus nephritis is kidney inflammation caused by systemic lupus erythematosus, occurring in up to 60% of SLE patients. It can lead to kidney failure if untreated. Treatment includes immunosuppressive medications such as mycophenolate, cyclophosphamide, and newer agents like voclosporin.
Clinical trials are advancing new treatments for lupus nephritis. Currently, 74 studies are recruiting a combined 225,998 participants across the United States. Research is being conducted by 59 organizations including Johns Hopkins University, Henry M. Jackson Foundation for the Advancement of Military Medicine, Washington University School of Medicine and 56 others.
2026 Lupus Nephritis Research Landscape
As of July 2026, the lupus nephritis clinical trial landscape includes 74 actively recruiting studies across 101 cities in the United States. These studies are collectively seeking 225,998 participants, with an average enrollment target of 3,054 per study.
The research spans multiple phases of development: 34 studies are in NA, 14 studies are in PHASE2, 5 studies are in PHASE1, 4 studies are in PHASE3, 3 studies are in PHASE4, 3 studies are in EARLY_PHASE1. The presence of Phase 3 trials indicates that some lupus nephritis treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 59 different organizations, including Johns Hopkins University, Henry M. Jackson Foundation for the Advancement of Military Medicine, Washington University School of Medicine, OvationLab, Sydney Local Health District, and 54 others. The large number of sponsors reflects significant research interest and investment in lupus nephritis treatment advancement.
Geographically, lupus nephritis trials are most concentrated in Atlanta, Georgia (7 trials); Boston, Massachusetts (7 trials); San Francisco, California (6 trials); Miami, Florida (6 trials); New York, New York (6 trials) and 7 other cities.
Featured Lupus Nephritis Studies
Highlighted recruiting studies for lupus nephritis, selected by enrollment size and research scope.
Critical Health Assessment and Outcomes Score/Study
CHAOS is based on the investigator's new and exciting results from pre-clinical and large longitudinal multi-center observational clinical studies of critically ill patients and asymptomatic community-based adults with little or no advanced disease. By integrating approaches from the physical, biological, computational, statistical and clinical sciences, this observational study will test the hyp...
SC2i Tissue and Data Repository Protocol
The purpose of this study is to collect samples of blood, urine, cerebrospinal fluid (CSF, the fluid that surrounds the brain and spinal cord), wound tissue and/or wound fluids, and other body fluids and tissues from people who have been seriously injured or ill. The samples will be used to develop and assess tests and/or tools that doctors can use to decide the best treatment plan for seriously i...
Embedded Palliative Care in the MICU
The goal of this study is to investigate whether embedding a hospice and palliative care practitioner within a medical intensive care unit will improve patient outcomes and healthcare usage. The practitioner will work solely within the medical intensive care units and offer timely as well as proactive consultations based on clinical criteria and estimated mortality risk. The study team will compar...
Frequently Asked Questions About Lupus Nephritis Clinical Trials
Are there lupus nephritis clinical trials near me?
Yes, there are 74 lupus nephritis clinical trials currently recruiting across 101+ cities in the United States, including Atlanta, Georgia; Boston, Massachusetts; San Francisco, California. Browse the studies above to find one at a location convenient for you.
How do I join a lupus nephritis clinical trial?
To join a lupus nephritis clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are lupus nephritis clinical trials free?
Yes, participation in lupus nephritis clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of lupus nephritis treatments are being studied?
Current lupus nephritis clinical trials are testing a range of approaches across NA (34 studies), PHASE2 (14 studies), PHASE1 (5 studies), PHASE3 (4 studies), PHASE4 (3 studies), EARLY_PHASE1 (3 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 59 research organizations.
Is it safe to participate in lupus nephritis clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 15, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 15, 2026 · Data from ClinicalTrials.gov