Los Angeles, CANCT05329441Now EnrollingIRB Ready

Depression in Adolescence Clinical Trial in Los Angeles, CA

Access cutting-edge depression in adolescence treatment through this clinical trial at a research site in Los Angeles. Study-provided care at no cost to qualified participants.

Sponsored by University of California, Los Angeles

Quick Self-Assessment

See if you qualify for this Los Angeles location

Preparing your pre-screening questions…

Expert Care in Los Angeles

Access depression in adolescence specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related depression in adolescence treatment provided free

Apply for This Los Angeles Location

Check if you qualify for this depression in adolescence clinical trial in Los Angeles, CA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Los Angeles

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Los Angeles site if eligible
  4. 4Begin participation

About This Depression in Adolescence Study in Los Angeles

Despite the prevalence and significant public health concern over depression among adolescents, up to 40% of depressed adolescents do not respond to first-line antidepressants (herein termed treatment non-response, TNR). The goal of this project is to recruit and assess 160 treatment-seeking depressed adolescents and test whether acute stress impacts peripheral levels of inflammation and downstream levels of glutamate in corticolimbic regions previously associated with depression, whether these stress-related biomarkers predict TNR to a 12-week trial of either fluoxetine or escitalopram, and whether these stress-related biomarkers predict 18-month clinical course.

Sponsor: University of California, Los Angeles

Who Can Participate

Inclusion Criteria

All sexes and genders
All ethnicities
Postpubertal (Tanner stage \> 3)
No medications that will interfere with the study (including antidepressants, mood stabilizers, hormone supplements, steroids, etc.) for at least 2-6 weeks (depending on exact medication)
Currently being seen by a clinician who will treat the participant with fluoxetine or escitalopram
The ability to provide assent, understand, and complete all study procedures
Caregiver consent (if applicable)

Exclusion Criteria

Primary mental health diagnosis other than a depressive disorder according to DSM-V
Any contraindications to MRI scanning, phlebotomy, or SSRI treatment
Stimulant usage
A concussion within the last 6 weeks or any lifetime concussion with loss of consciousness for at least 10 minutes
Any inflammatory conditions or use of anti-inflammatory medications that may influence study findings
Any major neurological or developmental disorders which could impact the participant's ability to comply with study procedure
Meeting for current or lifetime criteria of mania or psychosis, diagnosis of bipolar disorder, or any substance use disorders
First-degree relative with current, past, or suspected mania or psychosis

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Los Angeles?

Yes, this clinical trial (NCT05329441) has an active research site in Los Angeles, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Depression in Adolescence Treatment Options in Los Angeles, CA

If you're searching for depression in adolescence treatment options in Los Angeles, CA, this clinical trial (NCT05329441) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Los Angeles research site is actively enrolling participants for this clinical trial. You'll receive care from experienced depression in adolescence specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all depression in adolescence clinical trials near you to find additional studies recruiting in your area.

More Alzheimers Disease Trials in Los Angeles, CA

See all alzheimers disease clinical trials recruiting in Los Angeles — not just this study.

Browse Alzheimers Disease Trials in Los Angeles

Ready to Join in Los Angeles?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Los Angeles, CA