St Louis, MONCT06503809Now EnrollingIRB Ready

Diabetes Mellitus, Type 1 Clinical Trial in St Louis, MO

Access cutting-edge diabetes mellitus, type 1 treatment through this clinical trial at a research site in St Louis. Study-provided care at no cost to qualified participants.

Sponsored by Washington University School of Medicine

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Expert Care in St Louis

Access diabetes mellitus, type 1 specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related diabetes mellitus, type 1 treatment provided free

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Check if you qualify for this diabetes mellitus, type 1 clinical trial in St Louis, MO

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to St Louis

    Convenient for MO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit St Louis site if eligible
  4. 4Begin participation

About This Diabetes Mellitus, Type 1 Study in St Louis

Despite strong evidence that tight control of blood sugar reduces the risk of diabetes complications, most people with type 1 diabetes do not achieve recommended blood sugar targets. This randomized controlled trial will test whether a very-low- carbohydrate ketogenic diet can effectively and safely improve blood sugar control in adults with type 1 diabetes.

Sponsor: Washington University School of Medicine

Who Can Participate

Inclusion Criteria

Age ≥18 and ≤65 years
T1D diagnosed \>1 year prior to screening
HbA1c 7.0%-9.0%
Stable insulin delivery method for the past 30 days
Ability to read all device instructions and insulin pump settings
eGFR ≥60 mL/min/1.73 m2
Use of an insulin pump or insulin delivery by multiple daily injections
Use of personal CGM for at least 12 weeks and willing to change to Dexcom CGM for the duration of the study, if using a different sensor, to reduce variability in glucose values associated with different CGM products
Use of cellular phone with data capability for wireless connectivity to the CGM system.

Exclusion Criteria

Body mass index \<20.0 or \>34.9 kg/m2
Severe gastroparesis or history of bariatric surgery
Diabetes-related hospitalization (including for diabetic ketoacidosis or severe hypoglycemia) within 12 months of screening
Poorly controlled hypertension (SBP ≥160 mmHg or DBP ≥100 mmHg)
Taking diabetes medications, other than insulin (particularly SGLT2 inhibitors, which are associated with an increased risk of euglycemic DKA)
Structured exercise \>210 minutes per week
Pregnant, lactating, not using effective birth control if premenopausal, or planning to become pregnant within the 6-month study period
Unstable weight (\>4% change in the last 2 months)
Significant organ system dysfunction (e.g., severe pulmonary, renal, hepatic, or cardiovascular disease)
Anemia (Hgb \<10 g/dL)
Major psychiatric illness
Active tobacco use (\>8 cigarettes/day) or illegal drug use
Regular alcohol consumption (\>10 standard drinks per week)
Use of medications known to affect the study outcome measures or increase the risk of study procedures that cannot be temporarily discontinued for this study
Familial hypercholesterolemia
Active eating disorder
Dietary restrictions incompatible with a very-low-carbohydrate KD, vegan diet, vegetarian diet, severe lactose intolerance, severe aversion/sensitivity to eggs, fish, nuts, wheat, or soy, and any anaphylactic food allergy
Already consuming a low-carbohydrate (\<130 g/day) diet
Persons who are not able to grant voluntary informed consent
Persons who are unable or unwilling to follow the study protocol or who, for any reason, the research team considers an inappropriate candidate for the study.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in St Louis?

Yes, this clinical trial (NCT06503809) has an active research site in St Louis, MO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Diabetes Mellitus, Type 1 Treatment Options in St Louis, MO

If you're searching for diabetes mellitus, type 1 treatment options in St Louis, MO, this clinical trial (NCT06503809) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our St Louis research site is actively enrolling participants for this clinical trial. You'll receive care from experienced diabetes mellitus, type 1 specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all diabetes mellitus, type 1 clinical trials near you to find additional studies recruiting in your area.

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