Fort Worth, TXNCT05651204Now EnrollingIRB Ready

Dravet Syndrome Clinical Trial in Fort Worth, TX

Access cutting-edge dravet syndrome treatment through this clinical trial at a research site in Fort Worth. Study-provided care at no cost to qualified participants.

Sponsored by Cook Children's Health Care System

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Expert Care in Fort Worth

Access dravet syndrome specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related dravet syndrome treatment provided free

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Check if you qualify for this dravet syndrome clinical trial in Fort Worth, TX

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Fort Worth

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Fort Worth site if eligible
  4. 4Begin participation

About This Dravet Syndrome Study in Fort Worth

This study will non-invasively obtain levels of GABA in the brain of children with SCN1A+DS and neurodeveloping children through evoked and induced cortical responses, correlate them with the BOLD responses, and with the levels of GABA in their blood.

Sponsor: Cook Children's Health Care System

Who Can Participate

Inclusion Criteria

Authorized representative (parent/caregiver) must be willing and able to give informed consent for the participant's participation in the study. Participants capable of providing informed assent must be willing to provide their assent.
Participant and their parent/caregiver are willing and able (in the PI's opinion) to comply with all study requirements.
Participant is male or female aged between 0 months and 18 years of age, inclusive, at the time of consent.
Participant has a confirmed pathogenic or likely pathogenic SCN1A mutation, as demonstrated by genetic testing.
Participant had normal development prior to onset of first seizure as defined by the Centers for Disease Control and Prevention (CDC 2019).
Participant had an onset of seizures, defined as first focal clonic/hemiclonic, generalized/focal, generalized tonic-clonic/clonic, atonic, prolonged seizure, or status epilepticus between age 3 and 5 months, inclusive.
Participant should have an evaluation by a pediatric neurologist with a diagnosis of DS.

Exclusion Criteria

Participant has a copy number variant of SCN1A, including SCN1A microdeletion, affecting other genes.
Participant has an SCN1A mutation present on both alleles.
Participant has a known pathogenic or clinically suspected mutation in a seizure-associated gene besides SCN1A.
Participant has a confirmed mutation in a gene besides SCN1A, that is known to increase the severity of the seizure phenotype.
Participant has a known gain-of-function mutation, as defined by functional studies, including p.Thr226Met.
Participant has a history of notable developmental deficit that was evident prior to seizure onset, by physician report.
Participant has a known central nervous system structural abnormality as found on magnetic resonance imaging or computed tomography scan of brain which, in the opinion of the Principal Investigator (PI), is not consistent with the clinical phenotype of DS. Note: Prior scans may be used, and no new scan is required to confirm normal imaging.
Metal implants.
Baclofen pump.
Inability or unwillingness of patient or parent/legally authorized representative to give written informed consent (and/or assent as appropriate).

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Fort Worth?

Yes, this clinical trial (NCT05651204) has an active research site in Fort Worth, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Dravet Syndrome Treatment Options in Fort Worth, TX

If you're searching for dravet syndrome treatment options in Fort Worth, TX, this clinical trial (NCT05651204) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Fort Worth research site is actively enrolling participants for this clinical trial. You'll receive care from experienced dravet syndrome specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all dravet syndrome clinical trials near you to find additional studies recruiting in your area.

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