Nashville, TNNCT07172971Now EnrollingIRB Ready

Duchenne Muscular Dystrophy (DMD) Clinical Trial in Nashville, TN

Access cutting-edge duchenne muscular dystrophy (dmd) treatment through this clinical trial at a research site in Nashville. Study-provided care at no cost to qualified participants.

Sponsored by Larry W. Markham

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Expert Care in Nashville

Access duchenne muscular dystrophy (dmd) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related duchenne muscular dystrophy (dmd) treatment provided free

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Check if you qualify for this duchenne muscular dystrophy (dmd) clinical trial in Nashville, TN

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Nashville

    Convenient for TN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Nashville site if eligible
  4. 4Begin participation

About This Duchenne Muscular Dystrophy (DMD) Study in Nashville

This is a pharmacokinetic study (PK Study) to better understand empagliflozin dosing in pediatric Duchenne muscular dystrophy patients. Empagliflozin is currently used off-label in this population due to the mortality benefits seen in adult cardiomyopathy and heart failure. Investigators will perform PK studies in DMD patients of various ages and weights to better understand the PK profile (absorption, distribution, metabolism, excretion) and dosing to better treat Duchenne cardiomyopathy.

Sponsor: Larry W. Markham

Who Can Participate

Inclusion Criteria

Clinical phenotype of DMD confirmed with muscle biopsy or genotype
Presence of late gadolinium enhancement (LGE) imaging by CMR
Either normal or mildly depressed systolic function (LVEF\>40%)
≥8 years old and ≤18 years old

Exclusion Criteria

Current investigational therapy that may affect cardiovascular function
Additional genetic or congenital abnormality that may affect cardiovascular function or progression
Contraindication to or inability to undergo CMR
Symptomatic heart failure
History of ketoacidosis or hypersensitivity to SGLT2i therapy
Type 1 diabetes
Renal disease or history of frequent urinary tract infections or genitourinary skin infections

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Nashville?

Yes, this clinical trial (NCT07172971) has an active research site in Nashville, TN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Duchenne Muscular Dystrophy (DMD) Treatment Options in Nashville, TN

If you're searching for duchenne muscular dystrophy (dmd) treatment options in Nashville, TN, this clinical trial (NCT07172971) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Nashville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced duchenne muscular dystrophy (dmd) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all duchenne muscular dystrophy (dmd) clinical trials near you to find additional studies recruiting in your area.

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