Boston, MANCT05257681Now EnrollingIRB Ready

Emphysema or COPD Clinical Trial in Boston, MA

Access cutting-edge emphysema or copd treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Beth Israel Deaconess Medical Center

Quick Self-Assessment

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Expert Care in Boston

Access emphysema or copd specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related emphysema or copd treatment provided free

Apply for This Boston Location

Check if you qualify for this emphysema or copd clinical trial in Boston, MA

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Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Emphysema or COPD Study in Boston

The purpose of this protocol is to perform a pilot prospective controlled clinical trial to evaluate the potential role of lung fissure completion with pleural adhesiolysis strategy (experimental intervention) in severe emphysema/COPD patients with failed bronchoscopic lung volume reduction (BLVR) via the use of endobronchial valves (EBVs) therapy. In select patients, the lung fissure completion with adhesiolysis strategy will be performed by video-assisted thoracoscopic surgery (VATS) guided stapling along the lung fissures to reduce collateral ventilation with adhesions removal and determine whether this experimental strategy will improve outcomes after failed BLVR in patients with severe emphysema/COPD.

Sponsor: Beth Israel Deaconess Medical Center

Who Can Participate

Inclusion Criteria

Age 40 to 75 years.
Stable with less than 10mg prednisone (or equivalent) daily.
Nonsmoking for 4 months prior to screening and willing to not smoke during the study duration.
Current pneumococcus vaccination.
Current influenza vaccination.
Target lung volume reduction \<350ml after bronchoscopic lung volume reduction (BLVR).
Persistent dyspnea defined as an mMRC score greater or equal to 2 after bronchoscopic lung volume reduction (BLVR).
Endobronchial valves (EBV) are still in place.
Willing and able to complete protocol required study follow-up assessments and procedures.

Exclusion Criteria

Clinically significant (greater than 4 tablespoons per day) mucus production.
Myocardial infarction within 6 months of screening.
Decompensated heart failure.
Three or more pneumonia episodes in last year.
Three or more COPD exacerbation episodes in the last year.
Prior lung transplant, LVRS, bullectomy, or lobectomy.
Clinically significant bronchiectasis.
Unable to safely discontinue anticoagulants or platelet activity inhibitors for 7 days.
Uncontrolled pulmonary hypertension (systolic pulmonary arterial pressure \>45mmHg) or evidence or history of CorPulmonale as determined by a recent echocardiogram (completed within the last 3 months prior to screening visit).
Left ventricular ejection fraction (LVEF) less than 40% as determined by a recent echocardiogram (completed within the last 3 months prior to screening visit).
Resting bradycardia (\<50 bpm), Complex ventricular arrhythmia, sustained SVT.
PaCO2 greater than 50mmHg on room air at screening.
PaO2 less than 45mmHg on room air at screening.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT05257681) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Emphysema or COPD Treatment Options in Boston, MA

If you're searching for emphysema or copd treatment options in Boston, MA, this clinical trial (NCT05257681) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced emphysema or copd specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all emphysema or copd clinical trials near you to find additional studies recruiting in your area.

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