Jacksonville, FLNCT06280092Now EnrollingIRB Ready

Epilepsy Clinical Trial in Jacksonville, FL

Access cutting-edge epilepsy treatment through this clinical trial at a research site in Jacksonville. Study-provided care at no cost to qualified participants.

Sponsored by Sanjeet S. Grewal

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Expert Care in Jacksonville

Access epilepsy specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related epilepsy treatment provided free

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Check if you qualify for this epilepsy clinical trial in Jacksonville, FL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Jacksonville

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Jacksonville site if eligible
  4. 4Begin participation

About This Epilepsy Study in Jacksonville

This study is a non-randomized, open label, phase 1 clinical trial to evaluate the fesibility and safety of intrathalamic delivery of MSCs during standard of care DBS surgery for epilepsy. Subjects will be screened at our outpatient clinic and interested qualified subjects will be consented and offered participation in this trial. Once consent has been obtained, patients will undergo a standard preoperative evaluation which includes baseline laboratory values and a high-definition MRI. Patients will then undergo a stereotactic procedure for bilateral thalamic implantation of DBS leads through the ClearPoint® system. After the thalamic target for DBS is identified, cells will be infused directly into the anterior nucleus of the thalamus previous to lead implantation. Patients will be followed in the outpatient setting for up to a year after therapy application. Surgical, clinical, and radiographic data will be obtained during these visits

Sponsor: Sanjeet S. Grewal

Who Can Participate

Inclusion Criteria

Participants ≥ 18 years of age.
Participants with Drug Resistance Epilepsy as defined by the ILAE5.
Participants undergoing bilateral implantation of DBS leads into the anterior nucleus of the thalamus.
Adequate organ function as assessed by the following laboratory values within 3 weeks prior to admission to the study:
Serum creatinine and urea \< 2 times the upper limit of normal;
ALT, AST and alkaline phosphatase \< 3 times the upper limit of normal, and bilirubin \< 2.5 mg/dL;
Prothrombin time ≤ 1.5 times upper limit of normal;
INR and PTT ≤ 1.5 times the upper limit of normal;
Hemoglobin ≥ 9 g/dL;
Platelets ≥ 100 x 10\^9/L;
Absolute Neutrophil Count (ANC) ≥ 1.5 x 10\^9/L.
Patient or legal guardian is able to fully understand and provide written and verbal consent for the protocol.
Patient is a candidate for ANT DBS based on the following criteria established by the American Society for Stereotactic and Functional Neurosurgeons:
Confirmed diagnosis of epilepsy by an epileptologist with focal-onset seizures, with or without generalization;
Failure to adequately control seizures after two (or more) appropriate and adequately-dosed anti-seizure medications;
Either partial-onset seizures with a localized onset in a region not amenable to resection or following failed resective surgery or focal-onset seizures with distributed or unclear onset zone.

Exclusion Criteria

Patients who have undergone a prior intracranial procedure for epilepsy.
Patients with an intracranial tumor.
Confirmed pregnancy.
History of cancer not in remission for at least 5 years.
History of diabetes, chronic renal failure, or other significant underlying medical or ----immunosuppressive conditions.
History of drug or alcohol abuse.
Subjects allergic to any component of the investigational product.
Subjects \> 75 years of age.
Cognitively impaired adults.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Jacksonville?

Yes, this clinical trial (NCT06280092) has an active research site in Jacksonville, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Epilepsy Treatment Options in Jacksonville, FL

If you're searching for epilepsy treatment options in Jacksonville, FL, this clinical trial (NCT06280092) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Jacksonville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced epilepsy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all epilepsy clinical trials near you to find additional studies recruiting in your area.

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