NCT07766720 · ESM Technologies, LLC
Effects of Eggshell Membrane and Curcumin Extract Supplementation, Separately or Combined, on Recovery From Intense Exercise
What this study is about
Eggshell membrane and Curcumin supplementation prior to intense exercise may reduce inflammation, muscle and joint pain, and promote recovery. This proof-of-concept study will examine how ingestion of specially formulated versions of these nutrients affects recovery from intense exercise.
View original scientific description
Eggshell membrane and Curcumin supplementation prior to intense exercise may reduce inflammation, muscle and joint pain, and promote recovery. This proof-of-concept study will examine how ingestion of specially formulated versions of these nutrients affects recovery from intense exercise.
Interventions
DIETARY_SUPPLEMENT
NEM® brand eggshell membrane powder
500 mg/day of NEM® brand eggshell membrane powder in a single #0 capsule.
DIETARY_SUPPLEMENT
curQ+® brand highly absorbable curcumin
2,860 mg/day of curQ+® brand highly absorbable curcumin in a single 10 Oval softgel.
DIETARY_SUPPLEMENT
EM Placebo
500 mg/day of psyllium husk fiber powder in a single #0 capsule.
DIETARY_SUPPLEMENT
Curc Placebo
2,860 mg/day of coconut oil/polysorbate blend in a single 10 Oval softgel.
DIETARY_SUPPLEMENT
NEM® plus curQ+® combination
500 mg/day of NEM® brand eggshell membrane powder in a single #0 capsule PLUS 2,860 mg/day of curQ+® brand highly absorbable curcumin in a single 10 Oval softgel.
Primary outcome measures
VAS Muscle Soreness Rating
Time frame: 2 weeks
Changes in Visual Analog Scale (VAS) ratings of muscle soreness (rated from zero to 100 mm) from baseline following intense exercise. The higher the rating, the more muscle soreness so negative changes in VAS would equate to improvement.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Age 18 to 40 at the time of consent.
- Healthy and recreationally active.
- Ability to comply with study procedures.
- Agree to refrain from alcohol intake and use of non-steroidal anti-inflammatory (NSAIDS), aspirin, and other over-the-counter pain medications for 48 hours prior to and after completion of each testing session.
Exclusion criteria
- No recent history of exercise training
- An orthopedic limitation that would prevent the ability to perform the exercise intervention.
- Participants who currently smoke cigarettes.
- Known allergies to eggs, sulfur, or curcumin.
Where
- College Station, Texas
Collaborators
Exercise & Sport Nutrition Lab, Texas A&M University
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Aug 14, 2026 · Source of record for eligibility and locations