Bloomington, INNCT07420530Now EnrollingIRB Ready

Exercise-Induced Vocal Cord Dysfunction Clinical Trial in Bloomington, IN

Access cutting-edge exercise-induced vocal cord dysfunction treatment through this clinical trial at a research site in Bloomington. Study-provided care at no cost to qualified participants.

Sponsored by Indiana University

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Expert Care in Bloomington

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related exercise-induced vocal cord dysfunction treatment provided free

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Why Participate?

  • No-Cost Study Care

  • Local to Bloomington

    Convenient for IN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Bloomington site if eligible
  4. 4Begin participation

About This Exercise-Induced Vocal Cord Dysfunction Study in Bloomington

The overall objectives of the proposed research are to: 1. Evaluate the diagnostic validity of a novel mechano-acoustic signatures of task-characteristic activity during symptomatic and asymptomatic breathing in Exercise-Induced Laryngeal Obstruction (EILO) patients with the use of a novel miniature, soft wearable skin-mounted device, 2. Identify the mechanism/s of paradoxical respiratory control in EILO by quantifying the relationship between pulmonary mechanics, partial pressure of carbon dioxide (PCO2) maintenance, and vocal fold aperture prior to and during symptomatic and asymptomatic exercise ventilation, and 3. Identify unique biophysiological factors contributing to EILO among exercisers with and without EILO. Findings will be highly novel and clinically significant for early identification and management of EILO. For the study there are three separate visits: 1. Free running with the device on the neck 2. Exercise treadmill study 3. Undergoing MRI (Magnetic Resonance Imaging) of the vocal tract.

Sponsor: Indiana University

Who Can Participate

Inclusion Criteria

for Exercise-Induced Laryngeal Obstruction (EILO):
Physically active \>2.5 hours per week
Patients with EILO, as diagnosed by routine clinical examination by physician and/or speech language pathologist
Age range of 18-26 years
Greater difficulty breathing inside compared to out and difficulty breathing which is exacerbated at peak exercise and stops 1-5 minutes after exercise
Score of 7 or higher on the Dyspnea Index, which is a validated instrument to capture participant self-report of upper airway dyspnea symptoms.
Classified as low risk, based on the modified Physical Activity Readiness Questionnaire (PAR-Q) questionnaire, body mass index, and non-smoking status
Negative history of voice disorders, self-report of cognitive difficulties, asthma or other lung disease, cardiac disease, serious orthopedic injuries, current uncontrolled hypertension, illicit drug use, seizure/epilepsy, claustrophobia, use of beta blockers.
No metallic, mechanical or magnetic implants such as cardiac devices, cochlear, or other non-removable ear implants, any prosthesis, stents, deep brain stimulator, etc. Inclusion Criteria for Controls
Physically active \>2.5 hours per week
Age range of 18-26 years
Classified as low risk, based on the modified PAR-Q questionnaire, body mass index, and non-smoking status
Negative history of voice disorders, self-report of cognitive difficulties, asthma or other lung disease, cardiac disease, serious orthopedic injuries, current uncontrolled hypertension, illicit drug use, seizure/epilepsy, claustrophobia, use of beta blockers.
No metallic, mechanical or magnetic implants such as cardiac devices, cochlear, or other non-removable ear implants, any prosthesis, stents, deep brain stimulator, etc.

Exclusion Criteria

Individuals older than 26 years and younger than 18 years of age.
Women who are pregnant or could possibly be pregnant.
BMI \> 25 kg/m2
A 'yes' answer to any of the 14 questions on the PAR-Q pre-participation questionnaire
Current smoker
Positive history of voice disorders, self-report of cognitive difficulties, asthma or other lung disease, cardiac disease, serious orthopedic injuries, current uncontrolled hypertension, illicit drug use, seizure/epilepsy, claustrophobia, use of beta blockers.
Presence of metallic, mechanical or magnetic implants such as cardiac devices, cochlear, or other non-removable ear implants, any prosthesis, stents, deep brain stimulator, etc.
Do not report the following: Greater difficulty breathing inside compared to out and difficulty breathing which is exacerbated at peak exercise and stops 1-5 minutes after exercise Exclusion Criteria for Controls
Individuals older than 26 years and younger than 18 years of age.
Women who are pregnant or could possibly be pregnant.
BMI \> 25 kg/m2
A 'yes' answer to any of the 14 questions on the PAR-Q pre-participation questionnaire
Current smoker
Positive history of voice disorders, self-report of cognitive difficulties, asthma or other lung disease, cardiac disease, serious orthopedic injuries, current uncontrolled hypertension, illicit drug use, seizure/epilepsy, claustrophobia, use of beta blockers.
Presence of metallic, mechanical or magnetic implants such as cardiac devices, cochlear, or other non-removable ear implants, any prosthesis, stents, deep brain stimulator, etc.
Significant acute or chronic medical, neurologic, or illness in the patient that, in the judgment of the Principal Investigator, could compromise subject safety, limit the ability to complete the study, and/or compromise the objectives of the study

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Bloomington?

Yes, this clinical trial (NCT07420530) has an active research site in Bloomington, IN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Exercise-Induced Vocal Cord Dysfunction Treatment Options in Bloomington, IN

If you're searching for exercise-induced vocal cord dysfunction treatment options in Bloomington, IN, this clinical trial (NCT07420530) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Bloomington research site is actively enrolling participants for this clinical trial. You'll receive care from experienced exercise-induced vocal cord dysfunction specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all exercise-induced vocal cord dysfunction clinical trials near you to find additional studies recruiting in your area.

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